NIGHTTIME ROUTINE

21% SAVINGS compared to purchasing individually

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Buy One, Get One 70% OFF

Add any 2 of the same item to your bag.

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NIGHTTIME ROUTINE

21% SAVINGS compared to purchasing individually

Black Friday Promotion

Buy One, Get One 70% OFF

Add any 2 of the same item to your bag.

Discount applied automatically.

Black Friday countdown

Limited-time offer. While supplies last.

$364.00 Regular Price $462.00

Morning & Night Routine: SHOP HERE ►

Our skin loses moisture while we sleep. Use our high-performing nighttime routine to repair the day’s damage and promote the skin’s natural renewal process. The Nighttime Routine comes in our largest sizes for even more added value.

NIGHTTIME ROUTINE contains:

  • STEP 1: 1-Step Multi-Cleanse, 5.0 oz.
  • STEP 2 | FACE: 24/7 Barrier Balance Cream, 1.5 fl. oz.
  • STEP 2 | NECK: 6 Week Perfection Neck Cream, 1.5 fl. oz.
  • STEP 3: 8-in-1 BioSerum, 1.5 fl. oz.
  • SWEET DREAMS STEP: 100% Silk Pillowcase, King Size | 20 in x 36 in


DefenAge's innovative products work together to promote cell renewal, restore moisture and diminish the signs of aging, like fine lines and wrinkles, crepey skin, and hyperpigmentation. Perfect skincare for combination, dry, or oily skin. Embrace the power of nighttime skincare and give your skin the care it deserves, unlocking the secret to age-repair beauty.

All cosmetic products are made in the U.S.A.

DIRECTIONS

 

1-Step Multi-Cleanse

STEP ONE | 1-Step Multi-Cleanse

Daily: PM

Place dime-sized portion of cleansing gel onto fingertips. Gently massage over dry skin for 15 seconds. Moisten fingertips and massage using circular motions. Repeat until white cleansing milk develops. Rinse well with warm water. If desired, use a clean facecloth or cleansing sponge to remove excess cleanser. Pat dry with clean towel. Follow with STEP TWO (24/7 Barrier Balance Cream, and 6-Week Perfection Neck Cream).
Suitable for all skin types.

 

 

24/7 Barrier Balance Cream

STEP TWO - FACE | 24/7 Barrier Balance Cream

Daily: PM

Twice daily after cleansing, place up to 2 pumps of cream onto fingertips. While skin is still moist, lightly massage with fingertips over entire face. Avoid eye area. Wait 30 seconds; then apply STEP THREE (8-in-1 BioSerum).
Suitable for all skin types.

 

 

6-Week Perfection Neck Cream

STEP TWO - NECK | 6-Week Perfection Neck Cream

Daily: PM

Twice daily after cleansing, place 1 pump of the neck tightening cream onto fingertips. While skin is still moist, lightly massage cream onto the skin with short lifting motions using fingers of right hand to apply to left side of neck and décolleté, and vice versa. Start above breast line and work up to jawline and back of neck. Wait 30 seconds, then apply STEP THREE (8-in-1 BioSerum).
Suitable for all skin types.

 

 

8-in-1 BioSerum

STEP THREE | 8-in-1 BioSerum

Daily: PM

Apply after the 24/7 Barrier Balance Cream,
and 6-Week Perfection Neck Cream.

30 seconds after applying STEP TWO, place 1 pump of serum onto fingertips. While skin is still moist, lightly massage with fingertips first around eyes, then over entire face. Use a second pump on neck and décolleté. 
Suitable for all skin types.

DefenAge is proven in 19 clinical studies. All DefenAge formulas are dermatologist tested. 1-Step Multi-Cleanse and 8-in-1 BioSerum are also ophthalmologist tested.


Multi-center placebo-controlled double-blind clinical study shows that DefenAge “globally improves the visual appearance of aging skin” and “offers most of the advantages of time-honored retinols as well as newer but widely used growth-factor containing cosmeceuticals, without irritation or inflammation, sun-sensitivity, or concerns about neoplasia of the treated skin.”
Journal of Drugs in Dermatology 2018, 17(4): p. 426-441Amy Taub MD, Vivian Bucay MD, Gregory Keller MD, Jay Williams PhD, and Darius Mehregan MD

Learn More ►

 

KEY PERFORMANCE INGREDIENTS & TECHNOLOGIES

 

Age-Repair Defensins® | DefenAge's Exclusive

promotes new skin • anti-aging on a global scale

Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of "fresh" and young cells. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.

Niacinamide

hydration • firmness & elasticity • brightening

Soothes, revives the skin’s natural moisture barrier, renews the feel of skin firmness and elasticity, and brightens overall skin tone.

Hyaluronic Acid

Liposome Encapsulated (Cream) | Low Molecular Weight (Serum)

• hydration •

Promotes hydration and improves texture for remarkably smooth and even skin.

Fine Blend of Soothing and Calming Ingredients

• skin calming & soothing •

This product is infused with a powerful and concentrated composition of soothing and calming botanical molecules, including extract from the flowers of ‘love in a puff’, a medical plant known as a cortisone-free alternative, Epigallocatechin Gallatyl Glucoside, a water-soluble form of one of the most active molecules found in green tea, and black currant seed extract.

Ophiopogon Japonicus Root Extract and

Sinorhizobium Meliloti Ferment

skin's barrier balance • natural hydration

The powerful blend of natural extracts balances the skin’s barrier, saves the skin’s natural moisture, and promotes the levels of Natural Moisturization Factors (NMFs).

 

Squalene

moisturiozation • antioxidant 

Energizes skin hydration. Prevents moisture loss while restoring visible skin’s suppleness and flexibility. Fights skin damage and free radicals.

 

 

Panthenol

soothing • protection

Helps the skin build up a barrier against irritation and improves visible elasticity and smooth appearance. Hydrates the skin from within. Proven humectant.

 

 

Fine Blends of Natural Antioxidants, Enzymes

and Hydrating Technologies

antioxidants • hydration • soothing

Our “know-how”-protected, advanced and powerful blends of antioxidants and enzymes address environmental cell damage and defend against free radicals. They brighten, clarify and energize the skin for a revitalized radiance and luminosity.


CLEAN BEAUTY

This set contains seven of DefenAge’s top products; all of them are formulated based on the enhanced clean beauty standards. Find more information about our standards and why we raised the bar for skincare safety requirements on our Clean Beauty page.


GREEN PLANET

The bottles, tubes, and boxes are fully recyclable, please recycle.

Not tested on animals.


INGREDIENT LISTS

The detailed ingredient lists can be reviewed on the individual product pages:

 

24/7 Barrier Balance Cream ►

8-in-1 BioSerum ►

 


WARNINGS

For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.

 

QUALITY GUARANTEE

Quality guaranteed ONLY when sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old, or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay, or other unauthorized sources. 

 

MONEY BACK GUARANTEE

This product is qualified for the Money Back Guarantee.

In case of a refund, all products in this bundle should be returned.
Return Policy ►

 

No Questions

FREQUENTLY BOUGHT TOGETHER

Overall rating: 4.9223475 / 5 from 3902 reviews.

AI Generated Review Summary

Summary topics

Review topics: ["results","feels","skin","routine","looks","face","lines","cream","night"].

Review highlights

Reviews

Lightweight moisturizer for most skin types

"Lightweight moisturizer that works well as a day cream. I like that it is fragrance free and that the container twists close It moisturizes well in spring to fall northeast weather. For dry winters, I would recommend a thicker cream."

— HanNa W. (5/5)

Undecided

"I honestly don't know if this works better than just my moisturizer and step 3. I use it as step 2 followed by another product from them (step 3) and a great moisturizer. No breakouts and my face does stays hydrated. The amount the pumos puts out is not much so you may need another 1/4-1/2 pump for face bringing down onto your neck. I have thin, drier skin and I'm mature and need hydration so I'll take what I can get."

— Marlene M. (4/5)

Biosil8

"I really like this serum texture. I have been using now for several weeks. I see a difference in overall texture and brightness. This was my first purchase with the moisturizer. I liked it very much so purchased at a great sale the splendor set of products which gives you most of their products to try."

— Bernie (5/5)

Excellent morning routine

"I have fortuitously been introduced to the Defenage line of products. So far I’ve tried and love the 8 in 1 Bioserum, the lip product and the 2 minute reveal. I like this company’s customer service and although it’s pricey I stick up during their great sales. I’m 61 and people say I look a lot younger. Using and buying these products reminds me to stay out of the sun."

— Joanne C. (5/5)

Excited for long-term results

"This lasted about about 9 weeks using liberally twice a day. My neck has been the area that's really started showing its age, and I can definitely tell an improvement after going through my first jar. My skin isn't as crepey and laxity has improved. I'm curious to see how continued use will affect skin my skin's quality and appearance. I just repurchased and plan to keep this in my routine for as long as I can afford it."

— Sal (4/5)

The only face wash I use

"I’ve bought this so many times I’ve lost count. It cleans thoroughly without my face feeling tight after and has great slip."

— Gia V. (5/5)

Love this!

"Hydrating, smooth finish, and clinical evidence to support! Will forever be in my lineup."

— Margaret H. (5/5)

LOVE LOVE LOVE

"I have been using the neck cream for at least a few years and love it...I have actually started using it on my face as well and love how it absorbs in to my skin beautifully...I was using the Balance Cream then Serum on my face but the Balance Cream just never seems to absorb...So, now I use the neck cream followed by the Serum on my face."

— DanaT (5/5)

6 week Perfection creme

"I loved the feel of this creme and it was a good value for the money I spent."

— DEBBIE G. (4/5)

Good so far

"I havnt been using for more than a few weeks but u can see my skin tone getting lighter to my natural tone. Pores are minimizing and skin feels more hydrated and plump. Slightly minimizing fine lines but hoping to see more effective results for the fine lines"

— Corrine A. (5/5)

Q&A