NIGHTTIME ROUTINE

21% SAVINGS compared to purchasing individually

NIGHTTIME ROUTINE

21% SAVINGS compared to purchasing individually

$364.00 Regular Price $462.00

Morning & Night Routine: SHOP HERE

Our skin loses moisture while we sleep. Use our high-performing nighttime routine to repair the day’s damage and promote the skin’s natural renewal process. The Nighttime Routine comes in our largest sizes for even more added value.

NIGHTTIME ROUTINE contains:

  • STEP 1: 1-Step Multi-Cleanse, 5.0 oz.
  • STEP 2 | FACE: 24/7 Barrier Balance Cream, 1.5 fl. oz.
  • STEP 2 | NECK: 6 Week Perfection Neck Cream, 1.5 fl. oz.
  • STEP 3: 8-in-1 BioSerum, 1.5 fl. oz.
  • SWEET DREAMS STEP: 100% Silk Pillowcase, King Size | 20 in x 36 in


DefenAge's innovative products work together to promote cell renewal, restore moisture and diminish the signs of aging, like fine lines and wrinkles, crepey skin, and hyperpigmentation. Perfect skincare for combination, dry, or oily skin. Embrace the power of nighttime skincare and give your skin the care it deserves, unlocking the secret to age-repair beauty.

All cosmetic products are made in the U.S.A.

DIRECTIONS

 

1-Step Multi-Cleanse

STEP ONE | 1-Step Multi-Cleanse

Daily: PM

Place dime-sized portion of cleansing gel onto fingertips. Gently massage over dry skin for 15 seconds. Moisten fingertips and massage using circular motions. Repeat until white cleansing milk develops. Rinse well with warm water. If desired, use a clean facecloth or cleansing sponge to remove excess cleanser. Pat dry with clean towel. Follow with STEP TWO (24/7 Barrier Balance Cream, and 6-Week Perfection Neck Cream).
Suitable for all skin types.

 

 

24/7 Barrier Balance Cream

STEP TWO - FACE | 24/7 Barrier Balance Cream

Daily: PM

Twice daily after cleansing, place up to 2 pumps of cream onto fingertips. While skin is still moist, lightly massage with fingertips over entire face. Avoid eye area. Wait 30 seconds; then apply STEP THREE (8-in-1 BioSerum).
Suitable for all skin types.

 

 

6-Week Perfection Neck Cream

STEP TWO - NECK | 6-Week Perfection Neck Cream

Daily: PM

Twice daily after cleansing, place 1 pump of the neck tightening cream onto fingertips. While skin is still moist, lightly massage cream onto the skin with short lifting motions using fingers of right hand to apply to left side of neck and décolleté, and vice versa. Start above breast line and work up to jawline and back of neck. Wait 30 seconds, then apply STEP THREE (8-in-1 BioSerum).
Suitable for all skin types.

 

 

8-in-1 BioSerum

STEP THREE | 8-in-1 BioSerum

Daily: PM

Apply after the 24/7 Barrier Balance Cream,
and 6-Week Perfection Neck Cream.

30 seconds after applying STEP TWO, place 1 pump of serum onto fingertips. While skin is still moist, lightly massage with fingertips first around eyes, then over entire face. Use a second pump on neck and décolleté. 
Suitable for all skin types.

DefenAge is proven in 19 clinical studies. All DefenAge formulas are dermatologist tested. 1-Step Multi-Cleanse and 8-in-1 BioSerum are also ophthalmologist tested.


Multi-center placebo-controlled double-blind clinical study shows that DefenAge “globally improves the visual appearance of aging skin” and “offers most of the advantages of time-honored retinols as well as newer but widely used growth-factor containing cosmeceuticals, without irritation or inflammation, sun-sensitivity, or concerns about neoplasia of the treated skin.”
Journal of Drugs in Dermatology 2018, 17(4): p. 426-441Amy Taub MD, Vivian Bucay MD, Gregory Keller MD, Jay Williams PhD, and Darius Mehregan MD

Learn More

 

KEY PERFORMANCE INGREDIENTS & TECHNOLOGIES

 

Age-Repair Defensins® | DefenAge's Exclusive

promotes new skin • anti-aging on a global scale

Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of "fresh" and young cells. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.

Niacinamide

hydration • firmness & elasticity • brightening

Soothes, revives the skin’s natural moisture barrier, renews the feel of skin firmness and elasticity, and brightens overall skin tone.

Hyaluronic Acid

Liposome Encapsulated (Cream) | Low Molecular Weight (Serum)

• hydration •

Promotes hydration and improves texture for remarkably smooth and even skin.

Fine Blend of Soothing and Calming Ingredients

• skin calming & soothing •

This product is infused with a powerful and concentrated composition of soothing and calming botanical molecules, including extract from the flowers of ‘love in a puff’, a medical plant known as a cortisone-free alternative, Epigallocatechin Gallatyl Glucoside, a water-soluble form of one of the most active molecules found in green tea, and black currant seed extract.

Ophiopogon Japonicus Root Extract and

Sinorhizobium Meliloti Ferment

skin's barrier balance • natural hydration

The powerful blend of natural extracts balances the skin’s barrier, saves the skin’s natural moisture, and promotes the levels of Natural Moisturization Factors (NMFs).

 

Squalene

moisturiozation • antioxidant 

Energizes skin hydration. Prevents moisture loss while restoring visible skin’s suppleness and flexibility. Fights skin damage and free radicals.

 

 

Panthenol

soothing • protection

Helps the skin build up a barrier against irritation and improves visible elasticity and smooth appearance. Hydrates the skin from within. Proven humectant.

 

 

Fine Blends of Natural Antioxidants, Enzymes

and Hydrating Technologies

antioxidants • hydration • soothing

Our “know-how”-protected, advanced and powerful blends of antioxidants and enzymes address environmental cell damage and defend against free radicals. They brighten, clarify and energize the skin for a revitalized radiance and luminosity.


CLEAN BEAUTY

This set contains seven of DefenAge’s top products; all of them are formulated based on the enhanced clean beauty standards. Find more information about our standards and why we raised the bar for skincare safety requirements on our Clean Beauty page.


GREEN PLANET

The bottles, tubes, and boxes are fully recyclable, please recycle.

Not tested on animals.


INGREDIENT LISTS

The detailed ingredient lists can be reviewed on the individual product pages:

 

24/7 Barrier Balance Cream

8-in-1 BioSerum

 


WARNINGS

For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.

 

QUALITY GUARANTEE

Quality guaranteed ONLY when sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old, or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay, or other unauthorized sources. 

 

MONEY BACK GUARANTEE

This product is qualified for the Money Back Guarantee.

In case of a refund, all products in this bundle should be returned.
Return Policy

 

No Questions

FREQUENTLY BOUGHT TOGETHER

Overall rating: 4.923998 / 5 from 3842 reviews.

AI Generated Review Summary

Summary topics

Review topics: [skin, looks, cream, routine].

Review highlights

Reviews

Excellent!!

"I have been using this product for almost a year now, and the difference it makes is amazing, the cleaner takes all the make up off in one washing. I have used other products as well and the skin on my face and neck have shown remarkable results. This is a must for your facial routine"

mary s. (5/5)

So powerful must avoid during eyebrow tattoo and lip blushing

"This product works almost to well. Because of the effective cell turnover working so well and so rapidly, my permanent makeup artist has prohibited my Defenage for the 4 weeks following my tattoos. i miss the product and cant wait to get back to using it once my tattoos are fully healed."

Betsy P. (5/5)

Men Take Note

"This stuff really works. I am a 59 year old male. I have been very diligent since I turned 40 about not spending too much time in the sun as well as wearing SPF. Additionally, I have undergone different non surgical skin treatments to improve the elasticity and youthfulness of my face and neck (chemical peels, laser, micro needling and Morpheus8). Ever since I started using the entire DefenAge regime, I’ve noticed a difference in my skin tone and color. People comment all the time-“what are you doing to your face? It looks so healthy!”"

PHILIP D. (5/5)

Love the pump and smoother skin

"With a long next and décolletage it’s great to feel comfortable in my skin. We all know that our neck adds years if not cared for. I’ve never experienced any product that actually smooths my skin as well as the 6 Week Perfection Neck Cream. I stopped using it for a while and quickly noticed the difference when I added it back into my skincare routine. . it’s a much needed help for mature skin."

Jan H. (5/5)

Game-Changer for my Skincare

"I've been using 8-in-1 Bioserum for years, and I'm so happy with the results. I used to have very visible sun damage on my neck and decollete, but this product has all-but-eliminated the redness and roughness. I feel so good using the 8-in-1 Bioserum with the 24/7 Barrier Balance Creme (plus the 2-Minute Reveal)."

Christine M. (5/5)

My favorite face wash!

"One of my favorite products. I've been using this face wash for about 2 years and I have clearer skin, my makeup comes off easily, and my pores are smaller."

Catherine H. (5/5)

Exceptional Product!

"The DefenAge 8-In-1 Bioserum delivers as promised. The serum goes on smooth and feels light and luxurious. It immediately softens the skin and makes it feel exceptionally smooth. Using the serum evened out my skin tone and reduced pore size. My face has more elasticity and my skin looks firmer. My skin looks and feels healthier than it has in years. That's saying a lot for someone who is in her late sixties! I can see why the 8-In-1 Bioserum is a top-selling product."

Kim B. (5/5)

Fantastic product. This has replaced

"Fantastic product. This has replaced the multiple other products that I was using previously. My skin is smooth and moisturized after using this."

Ryan B. (5/5)

Great Product

"Great compliment to the regular 8-in 1. Early results show much improved neck area."

Travis W. (4/5)

Love the ingredients

"I don't know that I am seeing results but I believe in the product and technology of the product. It doesn not mix well with some other products as it or the other products pills on my face so just try it on a small area of your face first. The only thing I don't like is the price. My husband freaks out at the amount of money I spend on skincare. Sales would be nice!"

Marlene M. (4/5)

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