This product is covered by U.S. Patent No. 11,491,096.


This product is covered by U.S. Patent No. 11,491,096.

Eye Cream Award | NewBeauty Eye Cream Award

Technology-loaded anti-aging skincare treatment designed to address challenging cosmetic concerns for the skin around the eyes. Infused with breakthrough Age-Repair Defensins®

Read a dermatologist’s opinion and recommendations ►


  • •  Visibly lifts, firms, and smooths the upper eyelids.
  • •  Fades dark circles and diminishes the appearance of skin discoloration.
  • •  Reduces puffiness and "bumps" under the eyes.
  • •  Fades the appearance ofcrow’s feet and fine lines around the eyes.
  • •  Safe to apply to both the upper lid and under the eyes.
  • •  Can be used together with a retinol, if retinol is tolerated. Effective as a retinol alternative for retinol-sensitive skin.
  • •  Perfect as a standalone eye skincare; also recommended by dermatologists as a complement to aesthetic treatments, including skin resurfacing, microneedling, fractional lasers, and for post neuromodulator- and filler-injections around the eyes and upper face.
  • •  Free from irritants, suitable for all skin types, safe for contact lens wearers. 
  • •  Metal applicator with Cooling Tip Technology allows a clean, gentle, finger-free application, providing soothing benefits.
  • •  Award Winning Eye Cream - two awards: Named 2020 The Best Eye Cream for Dark Circles by NewBeauty Magazine and 2019 Eye Product of the Year by Beauty Independent Innovation Award.


Made in the U.S.A.



DefenAge® Beauty Brand

An award-winning beauty brand, DefenAge Skincare is endorsed by the world’s leading dermatologists. DefenAge’s professional-grade, age-repairing products are formulated to globally improve the visual appearance of aging skin for both women and men. DefenAge’s proprietary use of defensin-molecules is the signature difference. The company has also won three prestigious beauty awards for its innovations. DefenAge’s products can help improve visible skin density, the look of wrinkles and dark spots, and boost collagen production.



Opinions and Stories


Five Reasons Why The Skin Around Our Eyes Ages and How To Prevent It

by Wendy Lewis, award-winning writer

A few factors cause visible changes on the skin around the eyes and detractes a youthful appearance, including wrinkles, loss of skin elasticity, "bumps under eyes," and dark circles around eyes. Dermatologist, Jessica Weiser, MD explains, “One main reason the eye area is prone to premature aging is because this skin is significantly thinner than skin elsewhere on the face and body.”



Accelerate Anti-Aging With The Award-Winning Eye Radiance Cream From DefenAge

Wake up dormant skin cells to make brand-new, healthy cells with the eye cream from DefenAge, a premium skin care brand that formulates using proprietary Age-Repair Defensins. Scientifically-advanced skin rejuvenation products for the skin around the eyes from DefenAge include an award-winning eye cream and face serum, plus a fine cleanser.



3D Eye Radiance Cream

STEP TWO - EYES| 3D Eye Radiance Cream

Daily: AM | PM

After cleansing, while skin is still moist from rinsing, pump a drop of cream onto applicator. Lightly dab three dots of cream above and below each eye. Using applicator, massage cream around eyes.
Suitable for all skin types.




For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.


The 3D Eye Radiance Cream is ophthalmologist and dermatologist tested safe for contact lens wearers. Clinically proven effective. The 3D Eye Radiance Cream and its key defensin-based ingredient have been tested in 5 clinical studies.



The efficacy study of the 3D Eye Radiance Cream, including study design, raw data, results, and conclusions, are published in the peer-reviewed Journal of Cosmetic Dermatology (Berence, A., MD and Ghazizadeh, S., MD; 2020, p. 2000-2005); the clinical study protocols and study execution were reviewed and monitored by the University of California Los Angeles (UCLA) Institutional Review Board. The ophthalmology and irritation-safety studies were performed by a third-party clinical center (data on file). The concentration range of defensin-molecules infused into the Age-Repair Defensin® complex have also been tested in independent clinical safety studies. All clinical studies were conducted in US-based clinics located in California and New Jersey in accordance with federal and local regulatory requirements and Good Clinical Practice.

We are proud to report that all clinical studies returned an outstanding safety and efficacy product profile.



Age-Repair Defensins® | 1X | DefenAge's Exclusive

promotes new skin • anti-aging on a global scale

Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of "fresh" and young cells. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.

Hyaluronic Acid

• hydration •

Promotes hydration and improves texture for remarkably smooth and even skin.

Fine Blend of Natural Extracts, Antioxidants

and Soothing Technologies

antioxidants • brightening • soothing

Our “know-how”-protected, advanced and powerful blend of natural activities keeps the skin calm, addresses environmental cell damage, and visibly strengthens elastin. It energizes the skin for a revitalized radiance and luminosity and visibly decreases puffiness.


We thoughtfully formulated our eye cream to not use ingredients that might be harmful for our skin or body. Learn about our clean standards and the reasons why we develop them on our Clean Beauty page.

GREEN PLANET | DefenAge Beauty Brand

The bottle and box are fully recyclable, please recycle.

Not tested on animals.



3D Eye Radiance Cream

Water (Aqua), Glycerin, Cetyl Ethylhexanoate, Cyclopentasiloxane, Cetyl Esters, PEG-100 Stearate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Octyldodecanol, Butylene Glycol, Polyacrylate-13, Alpha-Defensin 5, Beta-Defensin 3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Ceramide NG, Sodium Hyaluronate, Albizia Julibrissin Bark Extract, Cynanchum Atratum Extract, Cardiospermum Halicacabum Flower/ Leaf/ Vine Extract, Darutoside, Leuconostoc/ Radish Root Ferment Filtrate, Rides Nigrum (Black Currant) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Helianthus Annuus (Sunflower) Seed Oil, Phospholipids, Tocopherol, Tocopheryl Acetate, Ubiquinone, l-Alanyl-l-Glutamine, Caprylic/Capric Triglyceride, Bisabolol, Tribehenin, PEG-10 Phytosterol, Dimethicone Crosspolymer, Dimethicone, Laureth-23, Laureth-4, Polyisobutene, Polysorbate 20, Carbomer, Sodium Benzoate, Potassium Sorbate, Lactic Acid, Disodium EDTA, Behenyl Alcohol, Albumin, Sodium Chloride.
Fragrance free.



Quality guaranteed ONLY when sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay or other unauthorized sources. 



This product is qualified for the Money Back Guarantee.
Return Policy ►


Is eye cream important?
The skin around your eye is thin, sensitive, and fragile, which is why your eyes are one of the first places on your face to show signs of aging. Eye-brightening cream is important to use to keep your eye skin young and resilient. When formulated with restorative ingredients and antioxidants, brightening under-eye cream can slow the signs of aging and prevent the breakdown of skin around the eyes without irritation.
What exactly does a radiant under-eye treatment do?
The under eyes do not have oil glands. This means the skin in this area can become easily dehydrated and damaged. What’s more, lifestyle factors, sun exposure, and more can weaken skin fibers and contribute to fine lines. While the main purpose of radiant eye cream is to prevent wrinkles and protect the skin around the eyes, a well-formulated dark circle cream can also reduce puffiness and prevent discoloration, contributing to a healthy, vibrant complexion. Eye cream is not a magic fix for eye wrinkles and bags, but it can optimize moisture and lead to healthier eye skin when used on a regular basis in conjunction with your skincare routine.
When should you start using a radiant under-eye treatment?
Don’t make the mistake of waiting until you see signs of aging to start using eye cream for dark circles. At this point, it will be too late to experience the preventative benefits of effective eye cream. The earlier you incorporate a radiance eye cream into your skincare routine, the more you’ll benefit from the effects. You can begin using eye cream in your daily skincare ritual as early as your late teens; most eye creams are beneficial for all ages and skin types.
What’s the best way to apply eye cream for dark circles?
When it comes to the skin around your eyes, the key is gentleness. With a small dollop of brightening under-eye cream on your pinky or ring finger (your weakest fingers), softly dab the cream into the skin around your eye socket and up to the brow bone. Take care not to get the cream in your lash line, as this can cause irritation. If the cream makes contact with your eyes, rinse thoroughly with water. You can repeat this process several times a day, preferably in the morning and at night.
During which step of my skincare routine should I apply eye cream for dark circles?
You want to apply our 3D Eye Radiance Cream after you have cleansed your skin and applied any other skin care products you would like to. Then take one pump of the 3D Eye Radiance Cream and dab 3 times below and 3 times above each eye. Then use the specially designed metal-tipped applicator to blend into the skin. Just do not get in the eyes or on the eye lashes. We recommend to layer our 8-in-1 BioSerum on top of our 3D Eye Radiance Cream for maximum results. This cream is ophthalmologist- and dermatologist- tested, safe for contact lens wearers, and suitable for all skin types.
What ingredients should I look for in an eye cream?
Most eye cream users have more than one skin concern. Luckily, our 3D Eye Radiance Cream is a multi-tasker that does the following to help tackle numerous eye area issues. Our 3D Eye Radiance Cream contains Age-Repair Defensins®, hyaluronic acid, a fine blend of natural extracts, antioxidants, and soothing technologies to help address various concerns.
What else can help with puffy eyes and dark under-eye circles?
In addition to regular use of a brightening under-eye cream, make sure to drink enough water and get enough sleep at night. Hydration and quality sleep are key to healthy, youthful skin. You should also strive to minimize your salt intake, so your skin doesn’t retain water. Cool compresses can also soothe puffy, inflamed eyes.
What causes dark circles?
Dark circles may actually be shadows that are cast by puffy eyelids. Sleep deprivation can cause fluid to build underneath your eye leading them to appear puffy. If your sleeping pattern is off from its normal routine, then this can cause dark circles as well. Age can also be a cause for dark circles because the dark blood vessels under your skin can become more visible causing this area to darken under the eyes. Straining your eyes can also be a cause. If you’re watching T.V. or staring at a computer screen for a long period of time, then this can enlarge the blood vessels around your eyes. Allergies can also trigger dark circles as well as being overly exposed to the sun. Dehydration is a common cause of dark circles as the skin under your eyes begins to look dull and your eyes look sunken.
Can eye cream reduce fine lines?
Yes! Our 3D Eye Radiance Cream visibly fades the appearance of crow's feet and fine lines around the eyes. It also lifts, firms, and smooths the upper eyelids, fades dark circles and diminishes the appearance of skin discoloration, and reduces puffiness and "bumps" under the eyes.
How long will it take to see results from 3D Eye Radiance Cream?
You can expect to see initial results from DefenAge products in one week with a full range of results occurring in six weeks.