evidence-based, revolutionary technology
#NewSkin   #ClinicallyProven


Can your skin naturally turn back the clock? According to a new study...YES!

Scientific research shows that a peptide, defensin, can reprogram our body to make skin visibly younger and younger every day. Scientists at DefenAge implemented this authentic revolutionary invention in DefenAge’s formulas that were tested and proven in rigorous clinical studies.

Our technology is patent-pending, exclusively available in DefenAge, does not belong to the growth factor category and can be combined with almost any skin care regimen.



Improvement on a global scale

study shows that skin can naturally turn back the clock




Multi-center placebo-controlled double-blind clinical study shows that DefenAge’s Clinical Power Trio “globally improves the visual appearance of aging skin” and “offers most of the advantages of time-honored retinols as well as newer but widely used growth-factor containing cosmeceuticals, without irritation or inflammation, sun-sensitivity, or concerns about neoplasia of the treated skin.”

Journal of Drugs in Dermatology 2018, 17(4): p. 426-441
Amy Taub MD, Vivian Bucay MD, Gregory Keller MD, Jay Williams PhD, and Darius Mehregan MD





Before and After Gallery

radical age correction



More Before and After photos



What Doctors Say About DefenAge


“DefenAge really represents a major advanced paradigm shift seen once per decade. The science is remarkable.”

Amy Taub, MD, Dermatologist, Illinois

“The clinical results put DefenAge into the best-in-class category for age-reversing skincare. This truly is a landmark product.”

Vivian Bucay, MD, Dermatologist, Texas

“DefenAge resulted in significant skin improvement to patient wrinkles, texture, pigmentations, and pores within six weeks without any remarkable side-effects.”

Gordon Sasaki, MD, FACS, California

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“Overall, my skin quality has improved 100%. ... As an esthetician of 25 years, I am so thrilled to have discovered DefenAge product.“

Alma Rose Middleton, Esthetician, California

“In six short weeks I experienced dramatic improvements in the radiance, texture, and appearance of my complexion. Defenage exceeded all of my expectations. Never before have I endorsed a product.“

E. L., Hawaii

“… I have had so many compliments on how good my skin looks and I owe it all to this product.“

Dana Hanse, California

“I have spent thousands on high end products and organic health store product natural solutions. This is the only product that doesn't cause my eyes to be puffy in the mornings. Everyone has commented on how great my skin looks.“

P.N., California


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DefenAge “is the next biggest game-changer in topical products for anti-aging.”


“The answer to aging is here. When used diligently, standout results can finally be achieved at home.”


“I've been going back and forth about getting Botox, but after starting this routine, I can hold off a little longer.”



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clinical study tested,
DefenAge’s core skin care regimen