20% SAVINGS compared to purchase individually

Earn 348 points in DefenAge® Skin Club with this purchase.


20% SAVINGS compared to purchase individually

Earn 348 points in DefenAge® Skin Club with this purchase.

/ $348.00 with free account /

Morning & Night Routine: SHOP HERE

Discover the importance of an AM skincare routine for radiant, healthy skin. A well-rounded morning routine sets the foundation for the day, replenishing moisture, enhancing your skin's natural glow, and shielding it from environmental stressors. Start your day right with the DefenAge skincare routine in the morning.

Powered by Age-Repair Defensin-molecules, this retinol alternative routine gives your eyes that radiant look to carry you throughout your day without retinol burn, irritation, or photosensitivity.


  • STEP 1: 1-Step Multi-Cleanse, 5.0 oz.
  • STEP 2 | FACE: 24/7 Barrier Balance Cream, 1.5 fl. oz.
  • STEP 2 | EYES: 3D Eye Radiance Cream, 0.5 fl. oz.
  • STEP 3: 8-in-1 BioSerum, 1.5 fl. oz.

The DefenAge Morning Routine is a complete summer-safe skincare regimen that synergistically works together to enhance your skin's health and beauty. Customers have found visible improvements in fine lines and wrinkles, hyperpigmentation, pore size, and crepey skin. Much like microneedling, Defensins help activate dormant new skin cells within the body to address the appearance of fine lines.

"Defensins deliver anti-aging results but they are not irritating like a retinol."

-Board-certified dermatologist Anne Chapas, M.D.

All products are made in the U.S.A.



1-Step Multi-Cleanse

STEP ONE | 1-Step Multi-Cleanse

Daily: AM

Place dime-sized portion of cleansing gel onto fingertips. Gently massage over dry skin for 15 seconds. Moisten fingertips and massage using circular motions. Repeat until white cleansing milk develops. Rinse well with warm water. If desired, use a clean facecloth or cleansing sponge to remove excess cleanser. Pat dry with clean towel. Follow with STEP TWO (24/7 Barrier Balance Cream, and 3D Eye Radiance Cream).
Suitable for all skin types.



3D Eye Radiance Cream

STEP TWO - EYES | 3D Eye Radiance Cream

Daily: AM

After cleansing, while the skin is still moist from rinsing, pump a drop of radiant under-eye treatment onto the applicator. Lightly dab three dots of dark circle eye cream below each eye. If not applying eye makeup, continue to apply to the upper eyelid, but avoid contact with eyes and eye lashes. Using the applicator, massage cream around the eyes.
Suitable for all skin types.



24/7 Barrier Balance Cream

STEP TWO - FACE | 24/7 Barrier Balance Cream

Daily: AM

After cleansing, place up to 2 pumps of cream onto fingertips. While skin is still moist, lightly massage with fingertips over entire face. Avoid eye area. Wait 30 seconds; then apply STEP THREE (8-in-1 BioSerum).
Suitable for all skin types.



8-in-1 BioSerum

STEP THREE | 8-in-1 BioSerum

Daily: AM

Apply after the 24/7 Barrier Balance Cream,
and 3D Eye Radiance Cream.

30 seconds after applying STEP TWO, place 1 pump of serum onto fingertips. While skin is still moist, lightly massage with fingertips first around eyes, then over entire face. 
Suitable for all skin types.

DefenAge is proven in more than 20 clinical studies. All DefenAge formulas are dermatologist tested. 1-Step Multi-Cleanse, 3D Eye Radinace Cream, and 8-in-1 BioSerum are also ophthalmologist tested.

Multi-center placebo-controlled double-blind clinical study shows that DefenAge “globally improves the visual appearance of aging skin” and “offers most of the advantages of time-honored retinols as well as newer but widely used growth-factor containing cosmeceuticals, without irritation or inflammation, sun-sensitivity, or concerns about neoplasia of the treated skin.”
Journal of Drugs in Dermatology 2018, 17(4): p. 426-441Amy Taub MD, Vivian Bucay MD, Gregory Keller MD, Jay Williams PhD, and Darius Mehregan MD

Learn More




Age-Repair Defensins® | DefenAge's Exclusive

promotes new skin • anti-aging on a global scale

Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of "fresh" and young cells. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.


hydration • firmness & elasticity • brightening

Soothes, revives the skin’s natural moisture barrier, renews the feel of skin firmness and elasticity, and brightens overall skin tone.

Hyaluronic Acid

Liposome Encapsulated (Face Cream) | Low Molecular Weight (Serum)

• hydration •

Promotes hydration and improves texture for remarkably smooth and even skin.

Sea Whip

• skin calming & soothing •

Keeps skin calm. Strongest, fastest, most effective soothing ingredient from the sea.

Ophiopogon Japonicus Root Extract and

Sinorhizobium Meliloti Ferment

skin's barrier balance • natural hydration

The powerful blend of natural extracts balances the skin’s barrier, saves the skin’s natural moisture, and promotes the levels of Natural Moisturization Factors (NMFs).


soothing • protection

Helps the skin build up a barrier against irritation and improves visible elasticity and smooth appearance. Hydrates the skin from within. Proven humectant.

Fine Blends of Natural Antioxidants, Enzymes

and Hydrating Technologies

antioxidants • hydration • soothing

Our “know-how”-protected, advanced and powerful blends of antioxidants and enzymes address environmental cell damage and defend against free radicals. They brighten, clarify and energize the skin for a revitalized radiance and luminosity.


This collection contains four of DefenAge’s top products; all of them are formulated based on the enhanced clean beauty standards. Find more information about our standards and why we raised the bar for skincare safety requirements on our Clean Beauty page.


The bottles, tubes, and boxes are fully recyclable, please recycle.

Not tested on animals.


The detailed ingredient lists can be reviewed on the individual product pages:


24/7 Barrier Balance Cream

8-in-1 BioSerum



For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.



Quality guaranteed ONLY when sold by or authorized professionals, otherwise it may be counterfeit, black market, old, or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay, or other unauthorized sources. 



This product is qualified for the Money Back Guarantee.

In case of a refund, all products in this bundle should be returned.
Return Policy


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