DefenAge's signature dermatologist recommended skin care treatment. We recommend starting DefenAge with the Clinical Power Trio. Trial sizes and plus-value edition are available.

/ $14 - $318 with free account,
$465 value /

This biologically-advanced serum provides an unprecedented concentration of defensin molecules in the Age-Repair Defensin^® Complex.

DefenAge's iconic best seller.

/ $56 -$198 with free account /

Intense hydrating cream infused with Age-Repair Defensins®, multi-action barrier balancing ingredients and skin brightening skincare actives.

/ $95.00 with free account /

Improves the visible health of delicate skin around the eyes. Technology-loaded treatment with extended performance.

Multi-award winner.

/ $95.00 with free account /

New luxe anti-aging neck tightening and moisturizing cream infused with leading scientific advances.

Trial size is available.

/ $9 - $95 with free account /

This rejuvenation-inspired, super-charged scalp serum revitalizes the environment surrounding the hair follicles, creating an optimal ecosystem for the follicles to flourish. Contains 48 natural proven ingredients.

/ $56 -$398 with free account /

First-ever defensin-containing cream for the hands and body! Multi-functional performance. The first of its kind. Experts recommend. Trial size is available.

/ $9 - $138 with free account /

In seconds, melt away surface debris, instantly dissolve heavy makeup and waterproof mascara, and help liquefy impurities in pores.

/ $39 - $46 with free account /

See amazing skin-brightening in minutes with this Triple Enzyme exfoliating mask. Instantly resurfaces, refines, and softens skin.

/ $55.00 with free account /

Our skin loses moisture while we sleep. Use our high-performing nighttime routine to repair the day’s damage and promote the skin’s natural renewal.

/ $380 with free account,
up to $679 value /

High-performing cosmetic treatment for the hands, elbows, knees, and ankles. Reverses signs of skin aging, premature aging, and sun damage.

/ $318 with free account,
$391 value /

A travel size of the CLINICAL POWER TRIO, DefenAge's core skincare regimen, a 2 week supply in DefenAge's signature cosmetic bag. TSA Friendly.

/ $95.00 with free account /

A trial size of the CLINICAL POWER TRIO, DefenAge's signature regimen, 2-3 day supply.

/ $14.00 with free account /

Luxurious sleep experience and beauty benefits. Natural 100% silk is less absorbent than cotton, helping skin retain valuable moisture while we sleep.

/ from $68.00 with free account /

An all-inclusive, luxury skincare regimen for the face and body in a trial-size, 2-3 day supply. Try them all!

/ $28 with free account /

Simple to use systems for skin-, scalp- and beard- care, developed for men. Jump start the skin with the Booster and maintain with the Provision. The 150K Hair Follicle Serum promotes sustainable health and wellness of the scalp and skin under the beard.

/ from $56 with free account /

A complete, professional-grade, annual skin detailing service tailored to men’s need. We recommend using the Booster once or twice a year to jumpstart the skin for high-performance and following with the Provision for skin maintenance until the next boost.

/ $134 with free account /

A scientifically proven, easy-to-use skincare system tailored and formulated directly to the unique needs of men’s skin. It is designed for daily skin maintenance and promotes healthy skin that looks fresh, energized, and young.

/ $98 with free account /

This rejuvenation-inspired, super-charged scalp and beard serum revitalizes the environment surrounding the hair follicles, creating an optimal ecosystem for the follicles to flourish. Contains 48 natural proven ingredients.

/ $56 -$398 with free account /