12-Factor Revitalizing Lip Enhancer
"I use this twice a day at least and sometimes more. It ensures that my lips never get dry and peel. Love, Love, Love this product!"
12-FACTOR REVITALIZING LIP ENHANCER
The complete lip care solution: visibly smooths, plumps, hydrates, and protects for softer, more youthful lips.
12-FACTOR REVITALIZING LIP ENHANCER
The complete lip care solution: visibly smooths, plumps, hydrates, and protects for softer, more youthful lips.
$74.00
12-Factor Revitalizing Lip Enhancer Details
Step into the future of lip care with DefenAge’s 12-Factor Revitalizing Lip Enhancer, a breakthrough serum designed to rejuvenate your lips from within. Unlike instant lip plumpers that deliver a short-lived effect, this advanced formula provides long-term benefits powered by DefenAge's exclusive Age-Repair Defensins®.
Key Features That Set Our Lip Enhancer Apart Include:
- • A True Anti-Aging Lip Treatment – Defensin-Powered Rejuvenation:
- • Stimulates your body's natural skin renewal process to produce fresh, youthful skin cells, leading to lasting improvements in lip volume and smoothness.
- • Promotes collagen production for firmer, more voluminous lips over time—without relying on temporary swelling or irritation.
- • 12 Active Factors for Complete Lip Care:
- • Offers a comprehensive solution, addressing hydration, repair, protection, and volume, unlike typical plumpers that focus solely on enhancing fullness.
- • Infused with antioxidants to shield lips from environmental damage, while also reducing the appearance of fine lines like “lipstick wrinkles" & "smoker's lines"
- • Non-Irritating, Gentle Formula; Needle-Free Solution:
- • Free from harsh irritants commonly found in instant plumpers, which can cause tingling or burning. Instead, it soothes and nourishes lips, delivering hydration and repair without discomfort.
- • No Needles, Just Results: Unlike invasive injectable treatments, this serum provides all the benefits of lip plumping and anti-aging without the pain or recovery time.
- • Luxurious Application Experience:
- • Packaged in an innovative airless bottle with a Zamac® ‘gold’ tip that provides a cooling, soothing effect during application, enhancing the experience without irritation.
- • Clinically Tested and Dermatologist Approved:
- • Developed with input from leading dermatologists, this serum is designed to deliver deep hydration, smooth lip contours, and restore softness for lips that feel and look more vibrant over time.
Get ready for lips that are not only soft and radiant, but also naturally fuller and youthful—with results that last!
Achieve Remarkable Lip Transformation
This unique formula revitalizes the overall health and appearance of your lips:
- • Boosts lip volume and firmness, creating a plumper, more defined appearance.
- • Infuses deep moisturization, hydrating away dullness and dryness, while leaving lips luxuriously soft and irresistibly smooth.
- • Visibly smooths fine lines and "lipstick wrinkles", for a youthful, rejuvenated look.
- • Supports the natural renewal process, revealing fuller, more vibrant lips that feel as youthful as they look.
- • Delivers powerful antioxidant defense, shielding lips from environmental stressors and keeping them healthy and radiant.
12 Factors in One
Each ingredient in our 12-Factor Revitalizing Lip Enhancer works synergistically to deliver noticeable, visible results. Here’s the secret behind this powerful formula:
- 1. Alpha-Defensin 5: The crowning jewel of the 12-Factor Revitalizing Lip Enhancer Alpha-Defensin 5 is DefenAge’s exclusive and innovative ingredient, formulated in the highest concentration achievable. This bio-synthesized molecule is celebrated for its ability to support natural age-repair pathways and encourage the development of new, younger-looking cells, making it a highly effective alternative to traditional retinol. Alpha-Defensin 5 advances the science of lip care by promoting a smoother, firmer, and more youthful appearance while remaining gentle and suitable for all skin types. It offers similar benefits to retinol-based serums but with a gentler, non-irritating approach.
- 2. Beta-Defensin 3: Supports collagen production, helps improve elasticity and firmness, and strengthens lip surface cells to retain valuable moisture.
- 3. Niacinamide (Vitamin B3): Soothes, hydrates, revitalizes the moisture barrier, and helps promote a uniform tone across the lips.
- 4. Panthenol (Vitamin B5): Helps maintain the integrity of the lip surface barrier, improves elasticity, and provides deep hydration for a smoother, firmer appearance.
- 5. A blend of Red Algae Extract and Tara Tree Fruit Extract: Helps reinforce the lips' barrier against environmental stressors, prolongs makeup wear, and provides immediate soothing comfort.
- 6. Organic Mustard Sprout Extract: Instantly hydrates and plumps lips, visibly reducing fine lines and enhancing natural lip definition and shape.
- 7. Ultra Filling Hyaluronic Acid Fine Spheres: Delivers long-lasting hydration, leaving lips smooth and elastic while reducing the look of fine lines.
- 8. Maximized Lip Peptide Complex: Moisturizes, firms, and smooths lips while enhancing definition and contour.
- 9. Brown Kelp Extract: Helps improve lip definition, hydration, and overall volume.
- 10. Butyrospermum Parkii (Shea) Butter: Boosts moisture, calms and soothes dry, chapped lips, leaving them smooth and supple.
- 11. Green-Tea Extract: A powerful antioxidant that helps protect lips from environmental aggressors and nourishes the delicate lip surface.
- 12. Extracts of 'Love in a Puff' flower and Black Currant seeds: A soothing, barrier-strengthening botanical complex that helps provide immediate comfort and protect lips from irritants.
Embark on your journey to softer, fuller, and more youthful lips with the 12-Factor Revitalizing Lip Enhancer — where cutting-edge science meets beauty to transform your lip care routine.
Expert Opinion:
"As a dermatologist, I see many lip plumpers that offer short-term results but can cause irritation or discomfort. The 12-Factor Revitalizing Lip Enhancer by DefenAge stands apart. Powered by exclusive Defensins, it provides anti-aging benefits that last beyond temporary plumping, without the harsh irritants commonly found in traditional plumpers. Instead, it soothes and nourishes the lips, delivering deep hydration and repair for a naturally fuller, healthier appearance."
– Dr. Natalie Curcio, Dermatologist
“This is a first-in-class product for the lips. Unlike a typical lip gloss or ointment, the DefenAge lip enhancer is a true skincare product that should be used as part of a complete regimen both morning and evening, and more during the day as desired. Like serums, moisturizers, eye products, and neck creams, the lip enhancer can be thought of as a comprehensive lip treatment.”
– Dr. Jessica Weiser, Dermatologist
“In my practice, I’ve seen many lip products, but the 12-Factor Revitalizing Lip Enhancer stands out as a true innovation in lip care. Unlike the temporary plumpers available today, this product targets the real signs of aging. Powered by Defensin-molecules, which are proven for their rejuvenating effects, it works from within to restore and renew lip health. With 12 carefully selected active factors designed for lip health and anti-aging, it’s the first of its kind to offer lasting improvements in lip texture, volume, and smoothness. Whether for prevention or addressing existing signs of aging, it offers a comprehensive, long-term solution for youthful lips.”
– Dr. Angela Bowers, Dermatologist
"I’ve tested the 12-Factor Revitalizing Lip Enhancer in my clinic, and it truly stands out. Unlike invasive injectable treatments, this serum offers the benefits of lip plumping and anti-aging without the pain or recovery time. Powered by Defensin-molecules, which activate the body’s natural rejuvenation pathways, it promotes the development of fresh, healthy skin cells. It soothes and nourishes the lips, delivering deep hydration and repair—without any discomfort. This is an excellent option for patients seeking a non-invasive yet effective solution for rejuvenating lip appearance."
– Dr. Gregory Keller, Plastic Surgeon, Professor of Surgery at UCLA
“Often, the lips are left out in the skin routine. The Lip Enhancer is a great addition to an already great facial skin care regimen by DefenAge. Luxurious, simple, effective. Great for all skin types to correct, maintain, and enhance one’s lips. Don’t let your lips age you.”
– Dr. Liza Kim, Plastic Surgeon
Opinions and Stories
DefenAge Skincare Launches the 12-Factor Revitalizing Lip Enhancer
Introducing a Revolutionary, First of Its Kind Anti-Aging Serum for Fuller, Smoother, More Youthful Lips. DefenAge Skincare is excited to announce the launch of its newest innovation, the 12-Factor Revitalizing Lip Enhancer. Powered by DefenAge's patented Age-Repair Defensins®, this groundbreaking lip serum is designed to rejuvenate lip appearance, smooth fine lines, and deliver intense hydration for a plumper, more youthful look. Read more...
Made in the U.S.A.
How to Use The 12-Factor Revitalizing Lip Enhancer
12-Factor Revitalizing Lip Enhancer Directions
Application Guide
1.
With the cap on, shake the bottle well before first use.
Take off the cap.
2.
Apply once or twice daily. Hold the bottle at the indented areas with 2 fingers. Push down on both sides of the applicator to release a drop of the serum.
3.
Use the tip of the applicator to smooth one pump over the lips.
DefenAge and Age-Repair Defensins® have been tested in more than 30 clinical studies, demonstrating the safety and efficacy of Defensin technology and DefenAge. The 12-Factor Revitalizing Lip Enhancer has also been evaluated by Board-Certified dermatologists and proven to deliver effective results.
12-Factor Revitalizing Lip Enhancer Ingredients
Key Performance Ingredients and Technologies
Alpha-Defensin 5
The crowning jewel of the 12-Factor Revitalizing Lip Enhancer Alpha-Defensin 5 is DefenAge’s exclusive and innovative ingredient, formulated in the highest concentration achievable. This bio-synthesized molecule is celebrated for its ability to support natural age-repair pathways and encourage the development of new, younger-looking cells, making it a highly effective alternative to traditional retinol. Alpha-Defensin 5 advances the science of lip care by promoting a smoother, firmer, and more youthful appearance while remaining gentle and suitable for all skin types. It offers similar benefits to retinol-based serums but with a gentler, non-irritating approach.
Beta-Defensin 3
Supports collagen production, helps improve elasticity and firmness, and strengthens lip surface cells to retain valuable moisture.
Niacinamide (Vitamin B3):
Soothes, hydrates, revitalizes the moisture barrier, and helps promote a uniform tone across the lips.
Panthenol (Vitamin B5):
Helps maintain the integrity of the lip surface barrier, improves elasticity, and provides deep hydration for a smoother, firmer appearance.
A blend of Red Algae Extract and Tara Tree Fruit Extract:
Helps reinforce the lips' barrier against environmental stressors, prolongs makeup wear, and provides immediate soothing comfort.
Organic Mustard Sprout Extract:
Instantly hydrates and plumps lips, visibly reducing fine lines and enhancing natural lip definition and shape.
Ultra Filling Hyaluronic Acid Fine Spheres:
Delivers long-lasting hydration, leaving lips smooth and elastic while reducing the look of fine lines.
Maximized Lip Peptide Complex:
Moisturizes, firms, and smooths lips while enhancing definition and contour.
Brown Kelp Extract:
Helps improve lip definition, hydration, and overall volume.
Butyrospermum Parkii (Shea) Butter:
Boosts moisture, calms and soothes dry, chapped lips, leaving them smooth and supple.
Green-Tea Extract:
A powerful antioxidant that helps protect lips from environmental aggressors and nourishes the delicate lip surface.
Extracts of 'Love in a Puff' flower and Black Currant seeds:
A soothing, barrier-strengthening botanical complex that helps provide immediate comfort and protect lips from irritants.
CLEAN SKINCARE
The cleanliness of our products is DefenAge’s philosophy. We do not use “convenient” ingredients that have compromised safety, and before we add any component into our formulas, we perform comprehensive research around it. To review the full list of ingredients that are excluded from DefenAge, please go to our Clean Beauty page. In addition, this product does not contain fragrance.
GREEN PLANET
We do not test products on animals.
INGREDIENT LIST
Caprylic/Capric Triglyceride, Water (Aqua), Bis-Diglyceryl Polyacryladipate-2, Ricinus Communis (Castor) Seed Oil, Hydrogenated Rapedseed Oil, Ethylhexyl Palmitate, Butyrospermum Parkii (Shea) Butter, Stearalkonium Hectorite, Pyrus Malus (Apple) Fruit Extract, Glycerin, Niacinamide, Sambucus Nigra Fruit Extract, Alumina, Glycine Soja (Soybean) Seed Extract, Propylene Carbonate, Phospholipids, Alpha-Defensin 5 (sh-Oligopeptide-109 SP), Beta-Defensin 3 (sh-Oligopeptide-108 SP), Undaria Pinnatifida Extract, Palmitoyl Tripeptide-1, Brassica Alba Sprout Extract, Epigallocatechin Gallatyl Glucoside, Spirodela Polyrrhiza Extract, Kappaphycus Alvarezii Extract, Caesalpinia Spinosa Fruit Extract, Bisabolol, Panthenol, Tocopheryl Acetate, Glycyrrhiza Glabra (Licorice) Leaf Extract, Citrus Limon (Lemon) Peel Extract, Methyl Glucose Sesquistearate, Albumin, Leuconostoc/Radish Root Ferment Filtrate, l-Alanyl-l-Glutamine, Polyglyceryl-2 Dipolyhydroxystearate, Glucomannan, Vanillin, Sodium Benzoate, Ubiquinone, Tetrahexyldecyl Ascorbate, Tocopheryl Nicotinate, Sodium Hyaluronate, Trihydroxystearin, Tribehenin, Sorbitan Isostearate, Potassium Sorbate, Citric Acid, Sodium Chloride.
Fragrance free.
J-247-2
12-Factor Revitalizing Lip Enhancer
QUALITY GUARANTEE
The quality of the 12-Factor Revitalizing Lip Enhancer is guaranteed ONLY when sold by defenage.com or authorized professionals; otherwise, it may be counterfeit, black market, old, or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay, or other unauthorized sources.
MONEY-BACK GUARANTEE
This 12-Factor Revitalizing Lip Enhancer product qualifies for the Money-Back Guarantee.
Return Policy ►
FREQUENTLY BOUGHT TOGETHER
