Defenage
"The 8 in 1 serum is very effective . I have been getting compliments on my skin tone and condition since I started using the product 10 years ago. It was recommended by a dermatologist and from a plastic surgeon"
DEFENAGE POWER PAIR
Anti-Aging Serum & Face Moisturizer
Visibly rejuvenate skin, reduce the appearance of fine lines and wrinkles, boost hydration, and enhance radiance
[ $296 value ]
[ $296 value ]
San Diego Boat Show Exclusive
Sun, salt air, and time on the water. Your skin absorbs it all and already knows how to recover. DefenAge gives it the signal.
27 % SAVINGS versus buying individually
Valid through June 28, 2026. While supplies last.
$304.00
Elevate your skincare with DefenAge’s Power Pair—two of our best-selling, dermatologist-recommended products designed to hydrate, protect, and rejuvenate the look of the skin. Powered by Defensin-molecule technology, this duo works together to reduce the appearance of fine lines, boost moisture retention, and restore your skin’s youthful glow. Ideal for all skin types, this simple, effective routine delivers initial visible results within the first week of use.
Key Benefits:
- • Age-Repair Defensins®: Triggers dormant skin cells to visibly reduce signs of aging.
- • Moisture Lock: Keeps skin deeply hydrated while enhancing its natural barrier.
- • Instant Radiance: Improves skin texture and luminosity for a glowing complexion.
- • Simplicity, Maximum Impact: Perfect for those seeking an easy-to-follow routine that delivers powerful results.
Routine Contents:
- • 8-in-1 BioSerum | Mega Size, 1.5 fl. oz.
- • 24/7 Barrier Balance Cream | Full Size, 1.5 fl. oz.
All products in this collection are supplied in original individual packaging.
Made in the U.S.A.
DIRECTIONS
24/7 Barrier Balance Cream
Daily: AM | PM
Twice daily after cleansing, place up to 2 pumps of cream onto fingertips. While skin is still moist, lightly massage with fingertips over entire face. Avoid eye area. Suitable for all skin types.
Suitable for all skin types.
8-in-1 BioSerum
Daily: AM | PM
After applying 24/7 Barrier Balance Cream, place 1 pump of 8-in-1 BioSerum onto fingertips. Lightly massage with fingertips first around eyes, then over entire face. Use a second pump on neck and décolleté. Follow with sunscreen.
Suitable for all skin types.
WARNINGS
For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.
Study on Defensins and Skin Rejuvenation: What It Means for You
Background:
Researchers conducted a multi-center, double-blind clinical trial to evaluate the effects of a skincare product containing alpha and beta Defensins—special molecules known for their role in skin healing and renewal. The goal was to see how effective these molecules are at rejuvenating aging skin.
What are Defensins?
Defensins are natural molecules found in the body, typically known for their role in immune defense. In this trial, they were tested for their ability to activate dormant skin cells (LGR6+ stem cells) to help generate new, healthy skin.
The Study:
- This was a double-blind, vehicle-controlled study, meaning neither the participants nor the researchers knew who was using the Defensin-containing product and who was using a placebo (vehicle).
- Participants included men and women with signs of skin aging, such as fine lines, wrinkles, uneven skin tone, and rough texture.
- They applied either the Defensin-containing product or a placebo product to their face for 6 weeks.
Key Results:
- Visible Improvement: Participants who used the Defensin-containing product showed significant improvement in skin quality compared to those who used the placebo. They experienced smoother skin, fewer wrinkles, improved texture, and a more even skin tone.
- Safety: The product was well-tolerated by participants, with no major side effects, making it a safe option for most people.
What This Means for You:
This study suggests that skincare products with Defensins can effectively help to rejuvenate aging skin by stimulating your skin’s natural renewal process. If you're looking for a beauty solution that works at a deeper, cellular level, Defensin-powered products like the ones from DefenAge could be a great addition to your skincare routine.
Please review the key performance ingredients and detailed ingredient lists on the individual product pages:
All formulas in this collection are fragrance-free.
CLEAN BEAUTY
We have carefully formulated our hand cream products to exclude multiple harmful and questionable ingredients. Please visit our Clean Beauty page for more details.
GREEN PLANET
The tubes and boxes are fully recyclable; please recycle.
Our products are not tested on animals.
QUALITY GUARANTEE
Quality guaranteed ONLY when sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old, or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay, or other unauthorized sources.
MONEY BACK GUARANTEE
This product is qualified for the Money Back Guarantee.
In case of a refund, all products in this bundle should be returned.
Return Policy ►
FREQUENTLY BOUGHT TOGETHER
[ $296 value ]
San Diego Boat Show Exclusive
Sun, salt air, and time on the water. Your skin absorbs it all and already knows how to recover. DefenAge gives it the signal.
27 % SAVINGS versus buying individually
Valid through June 28, 2026. While supplies last.