Luxurious facial cleanser with Natural Prebiotics.


  • •  Melts away surface debris in seconds, instantly dissolves heavy makeup and waterproof mascara, and helps liquefy impurities and air pollutants in pores.
  • •  Supports the skin's barrier.
  • •  Makes skin feel soft, hydrated and comfortable.
  • •  Natural prebiotics balance the skin's delicate ecology.
  • •  Enhances DefenAge's core defensin-technology.


Made in the U.S.A.



1-Step Multi-Cleanse

STEP ONE | 1-Step Multi-Cleanse

Daily: AM | PM

Place dime-sized portion of cleansing gel onto fingertips. Gently massage over dry skin for 15 seconds. Moisten fingertips and massage using circular motions. Repeat until white cleansing milk develops. Rinse well with warm water. If desired, use a clean facecloth or cleansing sponge to remove excess cleanser. Pat dry with clean towel.
Suitable for all skin types.


Ophthalmologist and dermatologist tested, safe for contact lens wearers. Clinically proven effective.



Natural Prebiotics

skin’s delicate ecology • healthy microbiome

Energizes the skin’s delicate ecology, supports healthy microbiome and restricts an expansion of “bad” bacteria. Designed to stimulate own defensins. Strengthens the skin's natural barrier.

"No Soap" - Technology

• skin's barrier protection •

Innovative technology promotes skin’s barrier function while efficiently cleaning skin. Leaves skin soft and hydrated.


DefenAge created our own standards for cleanliness of our products; they either exceed or match skincare industry practices. The full list of restricted ingredients that you will never find in DefenAge and other fundamental principles of DefenAge’s clean skincare can be explored on our Clean Beauty page.


The tube is fully recyclable, please recycle.

Not tested on animals.



1-Step Multi-Cleanse

Water (Aqua), Cocamidopropyl Hydroxysultaine, Sodium C14-16 Olefin Sulfonate, Alpha-Glucan Oligosaccharide, Panthenol, Saccharide Isomerate, Fructose, Glucose, Sucrose, Urea, Alanine, Aspartic Acid, Glutamic Acid, Dextrin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydroxypropyl Methylcellulose, Carbomer, Phenoxyethanol, Hexylene Glycol, Tetrasodium Glutamate Diacetate, Ethylhexylglycerin, Hexyl Nicotinate, Caprylyl Glycol, Sodium Hydroxide.
Fragrance free.



For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.



Quality guaranteed ONLY when sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay or other unauthorized sources. 



This product is qualified for the Money Back Guarantee.
Return Policy ►


Does DefenAge cleanser cause dryness?
Our 1-Step Multi-Cleanse is a truly very gentle cleanser, that does not cause skin irritation, dryness and leaves the skin feeling hydrated due to composition of proven ingredients. The cleanser does not contain any soap, therefore it is not damaging for skin's barrier and rather protects it.We also recommend using the 24/7 Barrier Balance Cream in conjunction with the cleanser that helps balance skin's barrier.