Journal of Drugs in Dermatology Acknowledges Defensins as a Pioneering Solution for Youthful Skin Rejuvenation
Carlsbad, CA – April 30, 2024 – DefenAge® Longevity Skincare, the manufacturer and distributor of revolutionary, evidence-based, de-aging products, is proud to announce the results of a new comprehensive clinical study of the line’s breakthrough ingredient Age-Repair Defensins® in it’s iconic best-selling product the 8-in-1 BioSerum.
As the product with the highest concentration of Defensin molecules, this new study1 by the Journal of Drugs in Dermatology (JDD) reaffirms the remarkable effectiveness of the Defensin-infused BioSerum as an innovative topical treatment for periocular wrinkles, commonly referred to as crow's feet.
Proprietary to DefenAge, Defensin-molecules are capable of boosting the rejuvenation of all layers of the skin, including the epidermis, dermis, and basal layer, and nourishing the skin’s blood supply, delivering essential nutrients and oxygen that are critical for promoting the look of healthy skin regeneration and visual improvement. In the epidermis and basal layer, Defensin-molecules reactivate latent LGR6 skin master cells to regenerate new basal stem cells and healthy keratinocytes in the skin, contributing to a refreshed, vibrant complexion. At the dermis layer, Defensin-molecules promote the activation of fibroblasts, stimulation of collagen and elastin, and boosting of the natural secretion of the body’s natural growth factors. When applied topically, these molecules reduce visible signs of all aspects of skin aging and promote a more youthful appearance.
The BioSerum is unique in its elevated concentration of Defensins, with increased concentrations of Alpha-Defensin 5 and Beta-Defensin 3 molecules, that trigger the body’s own cells to boost beautiful, healthier skin.
It is this innovative mechanism of action that elevates DefenAge from its competition. DefenAge is the only topical skincare brand that actually creates new, fresh skin as opposed to attempting to revitalize old, tired cells. The BioSerum along with all other DefenAge products pair well with other skincare products, ingredients and treatments, priming skin to respond more quickly and robustly and healing faster.
Adding to its impressive portfolio of more than 30 clinical trials, “this current study and the resultant data provide further, definitive evidence that the biometric Defensin formulation significantly improves periocular skin quality,” concludes the peer-review article. Improvements were noted in all aspects of skin quality including wrinkles, laxity, dyschromia, erythema, texture and radiance. Based on the Fitzpatrick-Goldman wrinkle scale, a statistically significant improvement was noted in both wrinkling and elastosis from baseline to day ninety in study participants. Eighty percent of subjects were rated by physicians as improved or much improved in a Global Aesthetic Improvement Scale (GAIS).
Clinical investigator and co-author of the JDD article Amy Forman Taub, MD, shares “The use of DefenAge 8-in-1 BioSerum around the eye area resulted in statistically significant improvements in the appearance of the skin’s roughness, wrinkling, redness, age spots, and pigmentation. DefenAge results in profound improvements in the visible health and beauty of the skin that are readily apparent to even the untrained eye.”
Like all DefenAge products, the 8-in-1 BioSerum is formulated with enhanced clean beauty and safety standards in mind and complies with DefenAge’s ban on any human- or animal- derived ingredients, cells or their parts, or media collected from living cells.
Find out more about this award-winning product at www.defenage.com.
1 Clinical Trial of Alpha and Beta Defensin Skin Care Regimen for Improvement of Periocular Wrinkles - September 2023 | Volume 22 | Issue 9 | 874 | Copyright © September 2023
About DefenAge®:
DefenAge is an American company founded in 2014 by a team of regenerative medicine experts whose anti-aging discovery became the heart and soul of its formulas. DefenAge’s products are widely recommended by dermatologists as a high-performing, de-aging cosmetic skin-, hair-, and nail-care. DefenAge’s proprietary Defensin-technology is named by medical professionals as the biggest skincare breakthrough for the last 50 years since the discovery of retinol’s benefits on the skin. DefenAge complies with or exceeds the Clean Beauty standards and its products have never been tested on animals. Honesty, transparency, and excelling in every way possible are the company’s standards.
