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HAND CARE ROUTINE
with 360-Rejuvenation Nail Root Serum
Give Your Hands the Five-Star Treatment!

25% SAVINGS compared to purchasing individually

LOW STOCK ALERT:  Ships by Thursday, 10/1.

HAND CARE ROUTINE

with 360-Rejuvenation Nail Root Serum
Give Your Hands the Five-Star Treatment!

25% SAVINGS compared to purchasing individually

LOW STOCK ALERT:  Ships by Thursday, 10/1.

$390.00 Regular Price $19.00
Claim Exclusive Rewards
SKU
10934-m

DefenAge Ultimate Hand Rejuvenation Routine With Nail Serum Details

Have you done your skin care routine today? Probably. Have you done your hand care routine today? Doubt it!

From sun damage & daily pollutants to dish-washing & harsh manicures, your hands and nails go through more than the rest of your body. Just like your face, your hands and nails age over time, meaning it requires extra special care and attention. In fact, they can start to show signs of premature aging sooner, which can include crepey skin.

The Hand Rejuvenation Routine With Nail Serum is a luxury manicure powered by Age-Repair Defensins®, which trigger young and healthy cells to produce fresh new skin. This hand and nail repair treatment helps revitalize dry, crepey skin on your hands all while visibly strengthening and hydrating your nails.

To make up for lost time from neglecting your hands, try the Ultimate Hand Rejuvenation.

The routine includes:

  • • 360-Rejuvenation Nail Root Serum Revitalizes nails via direct messaging to nail-producing cells creating visibly smoother fingernail ridges and a stronger, hydrated nail plate. This nail serrum is supplied in full size, 0.22 fl oz.
  • • 2-Minute Reveal Masque Gently removes dead skin cells to reveal fresh new skin and a brighter tone. It was named The Best Brightening Mask by NewBeauty Magazine. This hydrating mask is supplied in full size, 2.5 oz.
  • • 10 Luxe Hand & Body Cream Protects and restores lost moisture via multi-action activities and an advanced four-pillar revolutionary formulation. This moisturizing hand cream for crepey skin is supplied in full size, 10 fl. oz.
  • • 8-in-1 BioSerum Promotes new skin via 5-time concentrated Defensins and visibly renews the skin's firmness, elasticity, and texture. This enhanced serum is supplied in mega-size, 1.5 fl. oz.

Try this luxurious, three-step professional hand moisturizer routine for yourself. You could experience firmness in the skin's elasticity, brighter tone, and more hydrated skin in as little as 7-10 days.

All of the dry, crepey hand benefits as the original Hand Rejuvenation Routine PLUS:

  • •  Visibly improves natural health and the overall condition of the nails, nail root skin, and skin around the nails.
  • •  Improves natural nail smoothness.
  • •  Advances nail strength for less fragility.
  • •  Hydrates and nourishes nails and the surrounding skin.
  • •  Helps natural keratin production.
  • •  Provides a full range of antioxidant protection.
  • •  Optimizes nail growth metrics.

All of our moisturizing hand and nail products in the collection are supplied in their largest available sizes and in their original individual packaging.

All products are made in the U.S.A.

How To Use

How to Use Our Hand Repair Kit

Hand and Elbow Treatment Ritual

1-Step Multi-Cleanse

WEEKLY - Exfoliation

2-Minute Reveal Masque

1-2 Xs A Week

Once or twice a week after washing your hands, dry your skin thoroughly. Apply a dollop of the hydrating hand cream masque, about the size of a quarter, to both hands and the same amount of masque on both elbows. Using dry fingertips, gently massage the masque in a circular motion for 20 seconds or less, depending on skin sensitivity. Wait 2 minutes. With moistened fingertips, massage until the crystals are completely dissolved. Rinse treated areas thoroughly. We recommend applying the hand moisturizer masque on the elbows before showering for easy wash-off.
Not recommended for extremely sensitive or irritated skin.

3D Eye Radiance Cream

STEP TWO - Moisturizing

10 Luxe Hand & Body Cream

Daily: AM | PM

Once or twice daily, smooth onto skin as desired. For enhanced results, apply DefenAge 8-in-1 BioSerum to elbows, knees, back of hands and other targeted areas.

8-in-1 BioSerum

STEP THREE - New Skin

8-in-1 BioSerum

Daily: AM | PM

Apply after 10 Luxe Hand & Body Cream.

Thirty seconds after applying 10 Luxe Hand & Body Cream, distribute and massage 1 pump of serum between both hands and use another pump on both elbows. While the skin is still moist, lightly massage it into the skin. Follow with sunscreen.
Suitable for all skin types.

WARNINGS

These hydrating products are for external use only. Keep out of the eyes. If the product enters your eyes, rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.

Clinical Studies

Clinical Studies

All formulas in this collections has been tested by a Board Certified Dermatologist and shows an outstanding safety profile.

Please review clinical study on the individual product pages under the tab "CLINICAL STUDIES":

All formulas in this bundle are fragrance-free.

Ingredients

Hand Moisturizer Ingredients

Please review the key performance ingredients and detailed ingredient lists on the individual product pages:

All hydrating hand cream formulas in this bundle are fragrance-free.

CLEAN BEAUTY

We have carefully formulated our hand cream products to exclude multiple harmful and questionable ingredients. Please visit our Clean Beauty page for more details.

GREEN PLANET

The bottles, tubes, and boxes of these hand cream products are fully recyclable; please recycle.

Our hand moisturizers are not tested on animals.

Guarantees

Hand Repair Cream Guarantees

Quality Guarantee

The quality of our hand cream products is guaranteed ONLY when sold by defenage.com or authorized professionals; otherwise, it may be counterfeit, black market, old, or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay, or other unauthorized sources. 

MONEY-BACK GUARANTEE

These hand cream products qualify for the Money-Back Guarantee.

In case of a refund, all products in this bundle should be returned.

Return Policy ►
FAQ's
What makes the 10 Luxe Hand and Body Cream different from other body creams?
The 10 Luxe Hand and Body Cream is built around Age-Repair Defensins, the same technology behind DefenAge's face and neck products, now formulated for hands and body. Four pillars shape the formula: global anti-aging from the defensins themselves, barrier repair and natural moisturization from Ophiopogon japonicus root extract and Sinorhizobium meliloti ferment, soothing botanicals like panthenol, and a hero blend of niacinamide and squalane known to work well alongside defensins. It's a gentle, non-irritating alternative to retinol, absorbing quickly into a rich texture that never feels greasy on hands or body.
What are the key benefits of the 10 Luxe Hand and Body Cream?
The 10 Luxe Hand and Body Cream visibly firms and smooths the look of crepey skin while delivering both instant and long-lasting hydration, even in dry climates. It relieves the feeling of dryness and itching, balances the skin's barrier, and supports the skin's natural hyaluronic acid, laminin, and elastin. Over time it improves visible skin thickness and helps reverse signs of aging and sun damage, all while keeping skin feeling soft and glowing from hands to body.
Can the 10 Luxe Hand and Body Cream be used on both hands and body, including the neck and face?
Hands, arms, elbows, knees, and the rest of the body are all fair game for the 10 Luxe Hand and Body Cream, and the neck works well too. For the face, the 8-in-1 BioSerum and 24/7 Barrier Balance Cream remain the better fit, formulated specifically for facial skin.
Can I layer the 10 Luxe Hand and Body Cream with other products?
Layering the 10 Luxe Hand and Body Cream into an existing routine works beautifully, and results build even further with the 8-in-1 BioSerum added to elbows, knees, and the backs of the hands. Once or twice daily fits naturally into a morning and evening rhythm, with Defensin-molecules working alongside whatever else is already part of the routine to support noticeable improvement in tone, texture, and radiance. Sunscreen stays part of the daytime routine too, protecting all that progress along the way.
Are there enough Defensins in this formula to actually make a difference?
The 10 Luxe Hand and Body Cream contains the same Alpha-Defensin 5 and Beta-Defensin 3 technology used across DefenAge's face and neck products, built on seven years of research into how defensins perform compared to retinol. A 2022 study published in the Journal of Cosmetic Dermatology confirmed the cream improves overall skin quality, backing up what the formula delivers. Specific concentration levels stay proprietary across all DefenAge products, with clinical results doing the talking instead. Consistency matters most here, since the defensins work by activating the skin's own dormant cell reserves, with visible changes typically appearing within a week and the fuller range by six weeks.
Is the 10 Luxe Hand and Body Cream safe to use during pregnancy?
The 10 Luxe Hand and Body Cream was designed with clean beauty in mind, fragrance free and free from retinols along with many of the ingredients most commonly flagged during pregnancy. That said, formal clinical studies specifically evaluating safety during pregnancy or breastfeeding haven't been conducted, so consulting the ingredient list with an OB-GYN first is the safest way to know for sure. The full ingredient list is available on this page, and more on DefenAge's clean beauty standards can be found on the Clean Beauty page.
Will the 10 Luxe Hand and Body Cream help with sagging skin from weight loss?
Loose, crepey skin responds well to the 10 Luxe Hand and Body Cream, with Age-Repair Defensins supporting the skin's natural renewal and shea butter and barrier-repair ingredients restoring hydration and texture. For more significant skin laxity following major weight loss, pairing this cream with a body contouring procedure tends to bring the best results, with the cream supporting overall skin quality and firmness alongside whatever treatment is chosen.

FREQUENTLY BOUGHT TOGETHER

Overall rating: 5.0 / 5 from 1 reviews.

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Reviews

Started just a few weeks

"Started just a few weeks ago and already see improvement with my skin and hands. My skin is very sensitive and had no issues with these products."

— Heather M. (5/5)

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