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Black Friday! Our Biggest Sales Event! BOGO 70% Off. Shop Now!
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Black Friday! Our Biggest Sales Event! BOGO 70% Off. Shop Now!
Our Biggest Collection Savings Ever! 50% Off Splendor. SHOP NOW
Not sure where to start?
Take the quiz and we'll build a regimen made just for you.
Build Your Regimen
Set Descending Direction
  1. Splendor All-In-One Collection
    46% Savings
    SPLENDOR ALL-IN-ONE COLLECTION
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    2026 Holiday Promotion
    Our Best Collection Discount Ever!
    The epitome of visible results paired with an elegant, satisfying experience. Explore our ultimate collection, featuring every one of our award-winning skincare products.
    50% SAVINGS over buying individually!

    $572.00 Regular Price $1,144.00
  2. FLAWLESS FACE COLLECTION
    Limited Time
    FLAWLESS FACE COLLECTION
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    2026 Holiday Promotion
    A comprehensive facial care collection designed to hydrate, protect, and rejuvenate for luminous, youthful-looking skin. 
    40% SAVINGS over buying individually!

    $466.00 Regular Price $778.00
  3. DefenAge Power Pair: Anti-Aging Serum & Face Moisturizer
    Limited Time
    POWER PAIR
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    2026 Holiday Promotion
    Anti-Aging Serum & Face Moisturizer
    Legacy Formulation

    Visibly rejuvenate skin, reduce the appearance of fine lines and wrinkles, boost hydration, and enhance radiance.
    27% SAVINGS over buying individually!

    $221.00 Regular Price $304.00
  4. DefenAge Power Pair: Anti-Aging Serum & Face Moisturizer
    LIMITED TIME
    POWER PAIR - HYDRATION+
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    2026 Holiday Promotion
    Anti-Aging Serum & Face Moisturizer
    Hydration+ Edition

    Visibly smooth signs of aging, boost hydration, and support a stronger, healthier-looking skin barrier.
    27% SAVINGS over buying individually!

    $221.00 Regular Price $304.00
  5. DefenAge Power Pair: Anti-Aging Serum & Men's Face Moisturizer
    LIMITED TIME
    POWER PAIR - MENS EDITION
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    2026 Holiday Promotion
    Anti-Aging Serum & Face Moisturizer
    Men's Edition

    Visibly energize skin, reduce the appearance of fine lines and wrinkles, and boost hydration.
    27% SAVINGS over buying individually!

    $221.00 Regular Price $304.00
  6. Eye-conic Duo | 8-in-1 BioSerum, 3D Radiance Eye Cream
    LIMITED TIME
    EYE-CONIC PAIR
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    2026 Holiday Promotion
    Anti-Aging Serum & Eye Cream
    Visibly brighten tired-looking eyes, reduce the appearance of fine lines and wrinkles, and boost hydration.
    27% SAVINGS over buying individually!

    $221.00 Regular Price $304.00
  7. Eye & Lip Renewal Duo: Lip Enhancer & Eye Cream
    LIMITED TIME
    EYE AND LIP RENEWAL DUO
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    2026 Holiday Promotion
    Lip Enhancer & Eye Cream
    Ultimate care for delicate areas, visibly smooths and firms the skin around the eyes & lips.
    30% SAVINGS over buying individually!

    $126.00 Regular Price $180.00
  8. Smooth & Sculpt Neck Set: Neck Cream & Masque | 2026 Winter Collection
    LIMITED TIME
    SMOOTH AND SCULPT NECK SET
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    2026 Holiday Promotion
    Neck Cream & Masque
    Visibly lift, tighten, and smooth the neck & décolletage to restore a youthful appearance.
    30% SAVINGS over buying individually!

    $117.00 Regular Price $168.00
  9. 8-in-1 BioSerum Anti Aging Cream, 1.5 fl oz / 45 ml / Mega Size
    #1 Seller
    8-IN-1 BIOSERUM
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    An innovative, anti-aging serum bringing together 8 specialized serums in one.

    $198.00
  10. 24/7 BARRIER BALANCE CREAM - HYDRATION+
Advanced hydration, barrier support, and Defensin-powered age repair for skin that wants more moisture and comfort.
    2026 NEW
    24/7 BARRIER BALANCE CREAM - HYDRATION+
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    Advanced hydration, barrier support, and Defensin-powered age repair for skin that wants more moisture and comfort.

    $106.00
  11. Morning & Night Skincare Routine
    25% SAVINGS
    MORNING AND NIGHT ROUTINE
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A comprehensive morning & night skincare set to promote overall skin heath.

    $426.00 Regular Price $568.00
  12. Dermatologist Recommended Skin Care Clinical Power Trio - Fragrance Free
    CLINICAL POWER TRIO
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    DefenAge's signature dermatologist recommended skin care treatment.

    $328.00
  13. 24/7 Barrier Balance Anti-Aging Cream
    24/7 BARRIER BALANCE ANTI-AGING CREAM
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    An intense hydrating, barrier cream infused with Age-Repair Defensins® technology.

    $106.00
  14. 3D Eye Radiance Cream | Lifts & Firms Eye Area | DefenAge® Beauty Brand | Award Winning Skin Care Product for Eyes
    3D EYE RADIANCE CREAM
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    An illuminating eye cream infused with breakthrough Age-Repair Defensin® technology.

    $106.00
  15. Fragrance-free neck tightening cream by DefenAge designed to firm sagging skin and improve neck elasticity in 6 weeks
    6-WEEK PERFECTION NECK TIGHTENING CREAM
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A luxe anti-aging neck cream infused with leading age-repair technology.

    $106.00
  16. 12-Factor Revitalizing Lip Enhancer | Lip Gloss & Lip Plumper for Smoker's Lines
    12-FACTOR REVITALIZING LIP ENHANCER
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    The complete lip care solution: visibly smooths, plumps, hydrates, and protects lips.

    $74.00
  17. 7X Calming Complex
    7X CALMING COMPLEX
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A boosting treatment to defend your skin against hidden inflammation that accelerates aging.

    $74.00
  18. 10 Luxe Hand & Body Cream
    NEW 2.5X BIGGER
    10 LUXE HAND AND BODY CREAM
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A deeply hydrating, firming anti-aging lotion for hands and body.

    $168.00
  19. 360-Rejuvenation Nail Root Serum
    360-REJUVENATION NAIL ROOT SERUM
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A defensin-powered nail serum that promotes stronger, smoother, healthier nails and cuticles.

    $92.00
  20. DefenAge's exfoliating face masque revealing fresher, brighter skin for dry, dull, or aging skin types
    2-MINUTE REVEAL MASQUE
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A gentle, exfoliating face mask designed to reveal fresher, youthful-looking skin.

    $62.00
  21. DefenAge's 1-Step Multi-Cleanse facial cleanser that removes makeup using natural prebiotics without drying skin
    1-STEP MULTI-CLEANSE
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A luxurious, hydrating facial cleanser with natural prebiotics to melt away debris.

    $52.00
  22. Morning Skincare Routine
    21% SAVINGS
    MORNING ROUTINE
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A complete morning routine that replenishes moisture and boosts glow.

    $364.00 Regular Price $462.00
  23. Nighttime Skincare Routine
    21% SAVINGS
    NIGHTTIME ROUTINE
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    Nighttime routine that repairs daily damage and promotes natural skin renewal.

    $364.00 Regular Price $462.00
  24. Ultra Neck Perfection Treatment | NewBeauty Award Bundle | Email exclusive
    21% SAVINGS
    ULTRA NECK PERFECTION TREATMENT
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    Complete skincare set for the neck and décolletage, where aging shows most.

    $282.00 Regular Price $356.00
  25. Ultimate Hand Trio with the Nail Serum| DefenAge
    HAND CARE ROUTINE
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    Cosmetic hand treatment kit that reverses signs of skin aging and sun damage.

    $390.00 Regular Price $520.00
  26. Wedding Prep Skincare Routine
    22% SAVINGS
    WEDDING PREP ROUTINE
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A high-performing collection to relieve stressed skin and promote renewed skin cells.

    $370.00 Regular Price $472.00
  27. Fly Kit | Serum, Mask, Cream | Fragrance Free | DefenAge® Skincare | Two Week Trial Size | The Best New Skin Care
    FLY KIT
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A travel-size of the Clinical Power Trio, DefenAge's core regimen. Cosmetic bag included.

    $98.00
  28. DefenAge's fragrance-free skincare starter set with serum, cream, and masque for firmer, more radiant skin in 24 hours
    24-HOUR FAST STARTER KIT
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A trial size of the Clinical Power Trio, DefenAge's signature regimen.

    $19.00
  29. DefenAge Minis
    43% Savings
    DEFENAGE DISCOVERY MINIS
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    An all-inclusive trial-size, luxury skincare regimen for the face and body.

    $48.00 Regular Price $86.00
  30. DefenAge'a 150K Follicle serum for thinning hair to invigorate scalp and improve hair density
    150K HAIR FOLLICLE SERUM
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A super-charged scalp serum designed to help hair follicles flourish.

    $106.00
  31. Men's Skin Booster
    25% SAVINGS
    MENS SKIN BOOSTER
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A complete skin booster treatment tailored for men's skin needs.

    $178.00 Regular Price $239.00
  32. Men's Skin Care | Monthly Provision
    25% SAVINGS
    MENS SKIN PROVISION
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A scientifically proven, easy-to-use daily skincare system tailored for men’s skin.

    $118.00 Regular Price $158.00
  33. 24/7 Barrier Balance Cream - Men's Edition
    24/7 BARRIER BALANCE CREAM - MENS EDITION
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A clinically backed anti-aging barrier cream tailored to the unique needs of men's skin.

    $106.00
  34. 150K Hair Follicle Serum | Visible Rejuvenation | Best Hair Growth Serum Awards | Men's Edition
    150K HAIR FOLLICLE SERUM - MENS EDITION
    BLACK FRIDAY
    BOGO 70% OFF - Add 2 to Bag!

    A revitalizing scalp and beard serum that helps to stimulate stronger, fuller hair.

    $106.00
  35. 100% Silk Pillowcase | Mulberry Silk Pillowcase | A Silk Pillowcase Skin Care Regimen | DefenAge® Beauty Brand
    100% SILK PILLOWCASE

    A mulberry silk pillowcase designed for luxurious sleep and beauty benefits.

    $98.00
    Out of stock
  36. e-Gift Card | DefenAge® Skincare
    e-Gift Card

    Give the gift of DefenAge to your friends and family!

    From $20.00
Set Descending Direction