Unlock the Power of 8 Serums In 1. Shop Now!
Unlock the Power of 8 Serums In 1. Shop Now!
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Product Use

How fast can I see results?
Initial results can be seen in as little as 1 week, full range of results – 6 weeks. Why are a few days enough to see the first results with DefenAge?
It is enough because our unique cosmetic ingredient, the defensin-molecules, works together with the same “fresh” skin master cells that our body uses to heal wounds. Our skin heals scratches within a few days, meaning that it is enough for the body to produce a visible effect that fast. TIP: Exfoliate skin to see results faster. Remove old cells from the skin's surface to make new skin visible using an exfoliating mask. It also helps keep pores clean. DefenAge's exfoliation solution is the 2-Minute Reveal Masque, part of all our kits. It will take only 2 minutes, once or twice a week.
Can I combine DefenAge  with Retin-A or other skincare?
Yes, you can! This is a unique property of defensin-molecules, our core anti-aging technology. Due to an entirely different mechanism of action, DefenAge can be combined with almost any other skincare products and ingredients, including Retin-A and retinols, vitamin C, hyaluronic acid, and growth factors. The rule is simple: layer all other products in your skincare routine before layering DefenAge's Step 2 and 3.
How do I include DefenAge in my skincare routine with Retin-A, vit C etc?
The rule is simple: Apply Step 2 and Step 3 at the very end! DefenAge's Step 2 and 3 should be the last steps in your skincare routine; only sunscreen and makeup should be layered on top of our bioserum in the morning and nothing at night. This is the order for using the products that we recommend: STEP 1 - Cleansing: Facial cleanser, morning and evening. Please use any cleanser you like or DefenAge's 1-Step Multi-Cleanse. Exfoliate the skin after cleansinig with 2-Minute Reveal Masque once or twice a week. "ANYTHING ELSE" STEP: Any other skincare products that you would like to use, including vitamin C, Retin A/retinols etc. STEP 2 - Hydration: FACE: 24/7 Barrier Balance Cream on the face, except the skin around eyes; morning and evening. EYES: 3D Eye Radiance Cream for the skin around eyes; morning and evening. NECK: 6-Week Perfection Neck Tightening Cream for the skin on the neck; morning and evening. STEP 3 - New Skin: 8-in-1 BioSerum Anti-Aging Cream on the entire face including the skin around eyes and on the neck; morning and evening. SUNSCREN and MAKEUP in the morning.
Can I apply more product for more results?
Please use the exact quantity of the defensin products as we recommend: one pump per area (one pump rule). Do not overdose, more is not better. Our formulas are very well balanced and refined on concentrations of defensins and other ingredients to deliver results. USE: 24/7 Barrier Balance Cream: ONE (up to two) pumps on the face. 3D Eye Radiance Cream: ONE pump for both eyes. 6-Week Perfection Neck Tightening Cream: ONE pump on the neck and décolleté. 8-in-1 BioSerum: ONE pump on the face and ONE pump on the neck and décolleté.
Why should STEP 2 creams be layered before the 8-in-1 BioSerum?
In addition to stimulating new skin, defensins have an extra beneficial action to "close gaps" between cells on the surface of our skin. It means that defensins prevent water loss from the skin. The 8-in-1 BioSerum contains the highest concentration of defensins, meaning that once the serum is applied, penetration into the skin surface other products will be compromised (if "nothing/water goes out" - then "nothing is goes in"). This is a unique property of defensin molecules, therefore we always advise layering the 8-in-1 BioSerum as the last step of the skincare regimen, only sunscreen and makeup (if any) is recommended to be applied on top of the 8-in-1 BioSerum in the morning and nothing layered on top at night.  
Is DefenAge safe during pregnancy and breastfeeding?
We built our formulas with clean beauty in mind, our formulas are clean and do not contain most common harmful or questionable ingredients. In addition, please know that our formulas do not contain retinols. Unfortunately, we do not have formal clinical studies relating to safety during pregnancy and breastfeeding, therefore, before you start using DefenAge, we advise to consult the ingredient list with your OBGYN to be double sure. The detailed ingredient lists are shown on the product pages of our website.
Is 8-in-1 BioSerum good for acne prone skin?
Yes it is. The 8-in-1 BioSerum is safe for acne prone skin, our bio serum underwent multiple safety studies that returned an outstanding safety profile. Please be sure that you use the exact quantity of the product that we recommended, and do not exceed it: 1 pump of the bio serum for entire face and 1 pump on the neck.
How do I open bottles of the 24/7 Barrier Balance Cream and 8-in-1 BioSerum?
On the top of the bottles, there are directions in black lettering. Remove the white plug from the nozzle, hold the base of the bottle, then twist the top piece in a clockwise motion to open. The product should start dispensing after a few pumps.