I can only say when
"I can only say when I look at myself in the mirror, my eye area looks better, smoother appearing, no bags or puffiness, even with persistent crows feet, I'm older so I expect to see signs of aging from years of smiling : )."
This product is covered by U.S. Patent No. 11,491,096.



Technology-loaded anti-aging skincare treatment designed to address challenging cosmetic concerns for the skin around the eyes. Infused with breakthrough Age-Repair Defensins®.
Read a dermatologist’s opinion and recommendations ►
Made in the U.S.A.
An award-winning beauty brand, DefenAge Skincare is endorsed by the world’s leading dermatologists. DefenAge’s professional-grade, age-repairing products are formulated to globally improve the visual appearance of aging skin for both women and men. DefenAge’s proprietary use of defensin-molecules is the signature difference. The company has also won three prestigious beauty awards for its innovations. DefenAge’s products can help improve visible skin density, the look of wrinkles and dark spots, and boost collagen production.
DefenAge® 3D Eye Radiance Cream Selected as NewBeauty 2024 Readers’ Choice Award Winner
DefenAge® Skincare, the manufacturer and distributor of the leading evidence-based, age-repair skincare, is proud to announce that its 3D Eye Radiance Cream is a NewBeauty 2024 Readers’ Choice Award winner. This prestigious recognition is part of NewBeauty's second annual Readers’ Choice Awards, celebrating the products that resonate most with beauty enthusiasts. Read more...
DefenAge® Secures Four Wins at the 2024 Skincare Anarchy Top Picks Beauty Awards
DefenAge®, a leader in science-backed skincare solutions, proudly announces its wins in four categories in Skincare Anarchy’s 2024 Top Picks Beauty Awards. These awards celebrate the best in beauty products and recognize those that stand out for their scientific efficacy, excellence, and innovation. Read more...
Five Reasons Why The Skin Around Our Eyes Ages and How To Prevent It
by Wendy Lewis, award-winning writer
A few factors cause visible changes on the skin around the eyes and detractes a youthful appearance, including wrinkles, loss of skin elasticity, "bumps under eyes," and dark circles around eyes. Dermatologist, Jessica Weiser, MD explains, “One main reason the eye area is prone to premature aging is because this skin is significantly thinner than skin elsewhere on the face and body.”
Accelerate Anti-Aging With The Award-Winning Eye Radiance Cream From DefenAge
Wake up dormant skin cells to make brand-new, healthy cells with the eye cream from DefenAge, a premium skin care brand that formulates using proprietary Age-Repair Defensins. Scientifically-advanced skin rejuvenation products for the skin around the eyes from DefenAge include an award-winning eye cream and face serum, plus a fine cleanser.
After cleansing, while skin is still moist from rinsing, pump a drop of cream onto applicator. Lightly dab three dots of cream above and below each eye. Using applicator, massage cream around eyes.
Suitable for all skin types.
For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.
The 3D Eye Radiance Cream is ophthalmologist and dermatologist tested safe for contact lens wearers. Clinically proven effective. The 3D Eye Radiance Cream and its key defensin-based ingredient have been tested in 5 clinical studies.
STUDY DETAILS:
The efficacy study of the 3D Eye Radiance Cream, including study design, raw data, results, and conclusions, are published in the peer-reviewed Journal of Cosmetic Dermatology (Berence, A., MD and Ghazizadeh, S., MD; 2020, p. 2000-2005); the clinical study protocols and study execution were reviewed and monitored by the University of California Los Angeles (UCLA) Institutional Review Board. The ophthalmology and irritation-safety studies were performed by a third-party clinical center (data on file). The concentration range of defensin-molecules infused into the Age-Repair Defensin® complex have also been tested in independent clinical safety studies. All clinical studies were conducted in US-based clinics located in California and New Jersey in accordance with federal and local regulatory requirements and Good Clinical Practice.
We are proud to report that all clinical studies returned an outstanding safety and efficacy product profile.
Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of "fresh" and young cells. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.
Promotes hydration and improves texture for remarkably smooth and even skin.
Our “know-how”-protected, advanced and powerful blend of natural activities keeps the skin calm, addresses environmental cell damage, and visibly strengthens elastin. It energizes the skin for a revitalized radiance and luminosity and visibly decreases puffiness.
We thoughtfully formulated our eye cream to not use ingredients that might be harmful for our skin or body. Learn about our clean standards and the reasons why we develop them on our Clean Beauty page.
The bottle and box are fully recyclable, please recycle.
Not tested on animals.
Water, Glycerin, Cetyl Ethylhexanoate, Cyclopentasiloxane, Cetyl Esters, PEG-100 Stearate, Glyceryl Stearate, Octyldodecanol, Butylene Glycol, Polyacrylate-13, Phospholipids, Alpha-Defensin 5 (sh-Oligopeptide-109 SP), Beta-Defensin 3 (sh-Oligopeptide-108 SP), Albizia Julibrissin Bark Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Caprylic/Capric Triglyceride, Sodium Hyaluronate, Darutoside, Lueconostoc/Radish Root Ferment Filtrate, Cynanchum Atratum Extract, Rides Nigrum (Black Currant) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Ubiquinone, Bisabolol, Tocopherol, Tocopheryl Acetate, l-Alanyl-l-Glutamine, Dimethicone Crosspolymer, Dimethicone, Laureth-23, Laureth-4, Polyisobutene, Polysorbate 20, Carbomer, Sodium Benzoate, Potassium Sorbate, Behenyl Alcohol, Disodium EDTA, Lactic Acid, Albumin, Sodium Chloride.
Fragrance free.
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Quality guaranteed ONLY when sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay or other unauthorized sources.
This product is qualified for the Money Back Guarantee.
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This product is covered by U.S. Patent No. 11,491,096.