7X CALMING COMPLEX
Our Newest Innovation
A boosting treatment that combines the powers of anti-inflammation and age-defying technology to help soothe skin inflammation and discomfort.

7X Calming Complex
The 7X Calming Complex is an unmatched, fast-acting cosmetic skin treatment that combines the powers of anti-inflammation and anti-aging technologies. It helps soothe inflammation, visible redness, and discomfort while restoring a youthful appearance and protecting against stressors that commonly cause "inflamm-aging."
Inflamm-aging is a term experts use to describe chronic, unseen, low-grade inflammation that accelerates visible aging in the skin. This advanced formula provides benefits to reduce the effects of inflamm-aging with the power of our exclusive Age-Repair Defensins®.
Ideal for skin experiencing:
- • Visible Inflammation & Redness
- • Irritation & Sensitivity
- • Dryness & Flaking
- • Stress
- • Hormonal changes
- • Accelerated aging due to chronic, hidden inflammation
We recommend using the 7X Calming Complex in full for 10–14 days. This cosmetic treatment is best repeated 4–6 times per year to help calm, restore, and maintain balanced skin.
How Our Calming Complex Works:
The 7X Calming Complex is different than other formulas as it is designed to target inflamm-aging from within. Our patented Age-Repair Defensins® sparks the skin's rejuvenation process and boosts skin immunity to clear away irritating debris. The fine blend of calming ingredients targets soothing inflammation, redness, sensitivity, and reinforces the skin barrier. Together, these technologies strengthen skin’s resiliency for long-term comfort and balance.
- 1. Anti-Inflammation - A unique blend of eight evidence-based extracts help to calm compromised skin to reduce inflammation.
- 2 . Advanced Inflamm-Aging Defense Technology- Age-Repair Defensins® - our patented defensin technology works to restore the appearance of youthful skin quickly and promotes skin's natural defenses to clear away irritants.
- 3. Redness Relief - helps reduce redness caused by sensitive skin, hormonal changes, aging skin, harsh climates, dryness, environmental triggers, and irritation caused by retinoids.
- 4. Skin Resiliency & Environmental Skin Protection - protects and helps to restore the skin's barrier and shields skin against environmental pollutants, irritants, and allergens that commonly cause inflammation.
- 5. Multi-layered Hydration - delivers intense hydration and energizes skin while preventing moisture loss to wash away irritants from within.
- 6. Soothes and Comforts Irritated Skin - gently cools and calms stressed and sensitive skin to restore skin wellness.
- 7. Complexion Clarity & Even Tone - revives dullness to restore balanced, radiant skin.
DIRECTIONS
We recommend using the 7X Calming Complex in full for 10–14 days. Apply a pea-sized amount of serum to your fingertips and gently massage onto the face using light, upward motions. For the neck and décolleté, dispense an additional drop and smooth evenly. Use after your daily moisturizer and before applying the 8-in-1 BioSerum. Suitable for all skin types. This cosmetic treatment can be repeated 4–6 times per year to help calm, restore, and maintain balanced skin.
DefenAge and Age-Repair Defensins® have been tested in more than 30 clinical studies, demonstrating the safety and efficacy of Defensin technology and DefenAge.
7X Calming Complex Ingredients
Key Performance Ingredients and Technologies
Age-Repair Defensins® | 5X | DefenAge's Exclusive
promotes new skin • anti-aging on a global scale
- • Alpha-Defensin 5 - Targets natural wound-healing regeneration pathways, promoting the creation of new, youthful-looking skin
- • Beta-Defensin 3 - Reduces signs of inflammation and supports dermal regeneration for visibly renewed skin
Powerful Botanicals of Soothing and Calming Ingredients
addresses inflamm-aging • skin calming & soothing
- • Bai Wei Extract - Helps to suppress most common inflammation triggers to reduce signs of irritation
- • EGCGG (Green Tea Derivative) - Aims to decrease pro-infalmatopry internal signals to calm the appearance of inflammation
- • Love-in-a-Puff Extract - Cortisone-free botanical designed to suppress anti-inflammatory triggers
- • Arctic Waters Seaweed Extract - helps to reduce the impact of free radicals and soothe signs of reddened, irritated skin.
- • St. John's Plant Extract - renowned in traditional medicine for a wide range of powerful soothing and anti-inflammatory properties and reduction of redness and sensitivity.
- • Extra Pure Inner Leaf Aloe Vera - helps skin calm and reduce inflammation.
- • Native Sunflower Seed Oil - helps reduce skin redness and resolve inflammatory reactions.
Fine Blends of Natural Antioxidants, Enzymes and Hydrating Technologies
antioxidants • hydration • soothing
- • Natural Squalane & Apple Extract - Restores moisture balance and enhances suppleness
- • Phospholipids - Strengthen the skin's natural moisture barrier
- • BioOrganic Hyaluronic Acid - Delivers deep hydration and skin plumping
Skin Barrier Protection Extracts
Protection • Strengthening
Protects the skin's barrier and shields skin against environmental pollutants, irritants, and allergens that commonly cause inflammation
- • Red Algae Extract - Reinforces the skin barrier and supports resilience
- • Tara Tree Extract - Defends against environmental aggressors, pollutants, irritants, and allergens
CLEAN SKINCARE
The same as all other DefenAge products, the 7x Calming Complex is formulated with clean skincare in mind. To learn more about DefenAge’s clean standards, please visit our Clean Beauty page.
GREEN PLANET
We do not test products on animals.
INGREDIENT LIST
Water (Aqua), Aloe Barbadensis Leaf Juice, Sodium Polyacrylate, Octododecanol, Propanediol, Pyrus Malus (Apple) Fruit Extract, Glycerin, Butylene Glycol, Phospholipids, Beta-Defensin 3 (sh-Oligopeptide-108 SP), Alpha-Defensin 5 (sh-Oligopeptide-109 SP), Plankton Extract, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Caesalpinia Spinosa Fruit Extract, Laminaria Digitata Extract, Artemisia Vulgaris Extract, Rides Nigrum (Black Currant) Seed Oil, Kappaphycus Alvarezii Extract, Epigallocatechin Gallatyl Glucoside, Cynanchum Atratum Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Helianthus Annuus (Sunflower) Seed Oil, Sodium Hyaluronate, l-Alanyl-lGlutamine, Squalane, Tocopherol, Tocopheryl Acetate, Ubiquinone, Albumin, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, 1,2-Hexanediol, Sodium Chloride, Lecithin, Caprylhydroxamic Acid, Leuconostoc/Radish Root Ferment Filtrate.
QUALITY GUARANTEE
The quality of the 7X Calming Complex is guaranteed ONLY when sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay or other unauthorized sources.
MONEY BACK GUARANTEE
This 7X Calming Complex product qualifies for the Money-Back Guarantee.
Return Policy ►
BEST PAIRED WITH



Our Newest Innovation
A boosting treatment that combines the powers of anti-inflammation and age-defying technology to help soothe skin inflammation and discomfort.