FLAWLESS FACE COLLECTION
[ $736 value ]
2025 Holiday Promotion
40 % SAVINGS compared to purchasing individually
Limited-time offer. While supplies last.
TAKE AN ADDITIONAL
15 % OFF select Holiday Collections
With this offer, the collection is $375.70. Discount applied automatically in the cart.

Elevate your routine with the a complete set of skincare essentials. This all-in-one set includes everything needed for a complete face care regimen, from deep cleansing and targeted treatment to hydration, eye care, neck care, and lip enhancement. Powered by Defensin-molecule technology, each product works together to reduce the appearance of fine lines, improve skin texture, and restore a luminous, healthy glow—perfect for achieving your best skin yet this holiday season.
Key Benefits:
- • Age-Repair Defensins®: Awakens dormant skin cells to visibly reduce signs of aging.
- • Barrier-Boosting Hydration: Locks in moisture while strengthening the skin’s natural barrier.
- • Full-Face Renewal: Targeted treatments that visibly restore vulnerable and problem areas.
- • Simple, Powerful Skincare: Complete, results-driven skincare in one luxurious set.
- • Defends Against Inflamm-aging: Helps combat hidden inflammation that accelerates visible signs of aging.
Routine Contents:
- • 1-Step Multi-Cleanse (Mega Size, 5 fl.oz)
- • 8-in-1 BioSerum (MEGA Size, 1.5 fl. oz.)
- • 24/7 Barrier Balance Cream (Full Size, 1.5 fl. oz.)
- • 2-Min Reveal Masque (Full Size, 2.5 fl.oz)
- • 3D Eye Radiance Cream (Full Size, 0.5 fl.oz)
- • 6-Week Perfection Neck Cream (1.5 fl.oz.)
- • 12-Factor Revitalizing Lip Enhancer (Full Size, 0.25 fl.oz)
- • NEW 7X Calming Complex (Full Size, 0.5 fl.oz.)
DIRECTIONS
STEP 1 - Cleanse & Exfoliate
1-Step Multi-Cleanse
Daily: AM | PM
Place dime-sized portion of cleansing gel onto fingertips. Gently massage over dry skin for 15 seconds. Moisten fingertips and massage using circular motions. Repeat until white cleansing milk develops, then rinse with warm water or clean cloth.
2-Minute Reveal Masque
Once or Twice Weekly
After cleansing, dry skin thoroughly. Apply a quarter-size dollop of masque to face and jawline. Using dry fingertips, gently massage masque in a circular motion for 20 seconds or less depending on skin sensitivity. Avoid eye area. Wait 2 minutes. With moistened fingertips, massage until crystals are completely dissolved. Rinse face thoroughly.
STEP 2 - Moisturize & Treat Targeted Areas
24/7 Barrier Balance Cream
Daily: AM | PM
After cleansing or exfoliating, pump 1-2 pumps of cream onto fingertips. Lightly massage with fingertips over entire face. Avoid eye area.
3D Eye Radiance Cream
Daily: AM | PM
Place 1 pump of cream onto fingertips. Dab three dots of cream below each eye and lightly massage with the gold tip applicator. If not applying eye makeup, continue to apply to the upper eyelid, but avoid contact with eyes and eye lashes.
6-Week Perfection Neck Cream
Daily: AM | PM
Place 1-2 pump of neck tightening cream onto fingertips. Starting above the breast line and working up, lightly massage cream onto the décolleté, neck, and back of the neck with short, upward-lifting motions.
7X Calming Complex
Daily: AM | PM for 10-14 days or until tube is empty.
Apply a pea-sized amount of serum to your fingertips and gently massage onto the face using light, upward motions. For the neck and décolleté, dispense an additional drop and smooth evenly. This cosmetic treatment can be repeated 4–6 times per year to help calm, restore, and maintain balanced skin.
STEP 3
8-in-1 BioSerum
Daily: AM | PM
Wait 30 seconds after applying 7x Calming Complex, then apply a pea-size amount of serum onto fingertips. Lightly massage with fingertips first around eyes, then over entire face. Use a second drop on neck and décolleté. Follow with sunscreen.
STEP 4 - Finishing Product
Lip Revitalizing Lip Enhancer
Daily: AM | PM
With the cap on, shake the bottle well before first use. Hold the bottle at the indented areas with 2 fingers. Push down on both sides of the applicator to release a drop of the serum. Use the tip of the applicator to smooth one pump over the lips.
WARNINGS
For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.
Study on Defensins and Skin Rejuvenation: What It Means for You
Background:
Researchers conducted a multi-center, double-blind clinical trial to evaluate the effects of a skincare product containing alpha and beta Defensins—special molecules known for their role in skin healing and renewal. The goal was to see how effective these molecules are at rejuvenating aging skin.
What are Defensins?
Defensins are natural molecules found in the body, typically known for their role in immune defense. In this trial, they were tested for their ability to activate dormant skin cells (LGR6+ stem cells) to help generate new, healthy skin.
The Study:
- This was a double-blind, vehicle-controlled study, meaning neither the participants nor the researchers knew who was using the Defensin-containing product and who was using a placebo (vehicle).
- Participants included men and women with signs of skin aging, such as fine lines, wrinkles, uneven skin tone, and rough texture.
- They applied either the Defensin-containing product or a placebo product to their face for 6 weeks.
Key Results:
- Visible Improvement: Participants who used the Defensin-containing product showed significant improvement in skin quality compared to those who used the placebo. They experienced smoother skin, fewer wrinkles, improved texture, and a more even skin tone.
- Safety: The product was well-tolerated by participants, with no major side effects, making it a safe option for most people.
What This Means for You:
This study suggests that skincare products with Defensins can effectively help to rejuvenate aging skin by stimulating your skin’s natural renewal process. If you're looking for a beauty solution that works at a deeper, cellular level, Defensin-powered products like the ones from DefenAge could be a great addition to your skincare routine.
Please review the key performance ingredients and detailed ingredient lists on the individual product pages:
- 1-Step Multi-Cleanse ▸
- 24/7 Barrier Balance Cream ▸
- 3D Eye Radiance Cream ▸
- 6-Week Perfection Neck Cream ▸
- 8-in-1 BioSerum ▸
- 2-Minute Reveal Masque ▸
- 7X Calming Complex ▸
- 12- Factor Revitalizing Lip Enhancer ▸
CLEAN BEAUTY
We have carefully formulated our products to exclude multiple harmful and questionable ingredients. Please visit our Clean Beauty page for more details.
QUALITY GUARANTEE
Quality guaranteed ONLY when items are sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay or other unauthorized sources.
MONEY BACK GUARANTEE
This product is qualified for the Money Back Guarantee.
FREQUENTLY BOUGHT TOGETHER




[ $736 value ]
2025 Holiday Promotion
40 % SAVINGS compared to purchasing individually
Limited-time offer. While supplies last.
TAKE AN ADDITIONAL
15 % OFF select Holiday Collections
With this offer, the collection is $375.70. Discount applied automatically in the cart.