Defenage
"The 8 in 1 serum is very effective . I have been getting compliments on my skin tone and condition since I started using the product 10 years ago. It was recommended by a dermatologist and from a plastic surgeon"
25% SAVINGS compared to purchasing individually

The Ultimate Hand Trio is a unique and exclusive hand repair treatment that helps refresh the skin on your hands and elbows via topical application. This hand moisturizing routine uses DefenAge's Hero Blend of age-repairing Defensins, which trigger young and healthy cells to produce fresh new skin.
Maintaining a daily skincare routine for your hands is just as important as caring for the skin on your face. Since we do not apply makeup to our hands to offer protection, they can start to show signs of premature aging sooner, which can include crepey skin. The Ultimate Hand Trio for dry hands repairs, hydrates, and renews in 3 easy steps:
Try this luxurious, three-step professional hand moisturizer routine for yourself. You could experience firmness in the skin's elasticity, brighter tone, and more hydrated skin in as little as 7-10 days.
Here are additional benefits of our hand trio for dry hands.
All of our moisturizing hand products in the collection are supplied in their largest available sizes and in their original individual packaging.
All hydrating hand products are made in the U.S.A.
1-2 Xs A Week
Once or twice a week after washing your hands, dry your skin thoroughly. Apply a dollop of the hydrating hand cream masque, about the size of a quarter, to both hands and the same amount of masque on both elbows. Using dry fingertips, gently massage the masque in a circular motion for 20 seconds or less, depending on skin sensitivity. Wait 2 minutes. With moistened fingertips, massage until the crystals are completely dissolved. Rinse treated areas thoroughly. We recommend applying the hand moisturizer masque on the elbows before showering for easy wash-off.
Not recommended for extremely sensitive or irritated skin.
Daily: AM | PM
Once or twice daily, smooth onto skin as desired. For enhanced results, apply DefenAge 8-in-1 BioSerum to elbows, knees, back of hands and other targeted areas.
Daily: AM | PM
Apply after 10 Luxe Hand & Body Cream.
Thirty seconds after applying 10 Luxe Hand & Body Cream, distribute and massage 1 pump of serum between both hands and use another pump on both elbows. While the skin is still moist, lightly massage it into the skin. Follow with sunscreen.
Suitable for all skin types.
These hydrating products are for external use only. Keep out of the eyes. If the product enters your eyes, rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.
All formulas in this collections has been tested by a Board Certified Dermatologist and shows an outstanding safety profile.
Please review clinical study on the individual product pages under the tab "CLINICAL STUDIES":
All formulas in this bundle are fragrance-free.
Please review the key performance ingredients and detailed ingredient lists on the individual product pages:
All hydrating hand cream formulas in this bundle are fragrance-free.
We have carefully formulated our hand cream products to exclude multiple harmful and questionable ingredients. Please visit our Clean Beauty page for more details.
The bottles, tubes, and boxes of these hand cream products are fully recyclable; please recycle.
Our hand moisturizers are not tested on animals.
The quality of our hand cream products is guaranteed ONLY when sold by defenage.com or authorized professionals; otherwise, it may be counterfeit, black market, old, or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay, or other unauthorized sources.
These hand cream products qualify for the Money-Back Guarantee.
In case of a refund, all products in this bundle should be returned.
Return Policy ►
25% SAVINGS compared to purchasing individually