Plentiful in connective tissue throughout the body, including the dermis, these cells produce the collagen and elastin responsible for keeping skin pliant and springy. Topical retinoids ramp up collagen production in fibroblasts. A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, produces the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.
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