Dna Repair Enzymes
Proven to correct the UV-induced DNA damage underlying wrinkles, brown spots, and skin cancer, these liposomally encapsulated marine extracts break the abnormal bonds forged by UV light, causing atoms in our DNA to resume their normal positions. In a study published in The Lancet in 2001, 30 subjects with a rare genetic disorder predisposing them to skin cancer applied a lotion with DNA repair enzymes daily for one year. At the trial’s end, they saw a 68 percent reduction in the development of precancerous lesions, and 30 percent fewer basal cell carcinomas. DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs). This can eventually lead to malignant tumors, or cancer as per the two hit hypothesis.
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