This naturally occurring amino-acid pairing quells damaging inflammation, glycation, and free-radical activity, and levels of it in our bodies decline with age. Some research indicates that oral supplements and topical creams containing it can stave off premature wrinkling, collagen breakdown, and thinning of the skin. a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues.[citation needed] Carnosine was discovered by Russian chemist Vladimir Gulevich.

Carnosine is naturally produced by the body in the liver from beta-alanine and histidine. Like carnitine, carnosine is composed of the root word carn, meaning "flesh", alluding to its prevalence in meat. There are no plant-based sources of carnosine. Carnosine is readily available as a synthetic nutritional supplement.

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