This product is covered by U.S. Patents No. 11,491,096 and 11,020,452.

How fast can I see the initial results
when using DefenAge?
Initial results can be seen in as little as
Full range of results – 6 weeks.


This product is covered by U.S. Patents No. 11,491,096 and 11,020,452.

How fast can I see the initial results
when using DefenAge?
Initial results can be seen in as little as
Full range of results – 6 weeks.

This kit is a travel size of the CLINICAL POWER TRIO, DefenAge's core skincare regimen, a 2 week supply in DefenAge's signature cosmetic bag. TSA Friendly.


The Fly Kit contains:

  • •  2-Minute Reveal Masque | Net Wt. 0.75 oz.
  • •  24/7 Barrier Balance Cream | 0.5 fl. oz.
  • •  8-in-1 BioSerum | 0.33 fl. oz.
  • •  Cosmetic bag


Optionally, use this kit for a 2-week trial. Preview your long-term results while enjoying initial savings. 


All cosmetic products are made in the U.S.A.



24/7 Barrier Balance Cream

STEP TWO | 24/7 Barrier Balance Cream

Daily: AM | PM

Twice daily after cleansing, place a pea-size amount of cream onto fingertips. While skin is still moist, lightly massage with fingertips over entire face. Avoid eye area. Wait 30 seconds; then apply STEP THREE (8-in-1 BioSerum).
Suitable for all skin types.



8-in-1 BioSerum

STEP THREE | 8-in-1 BioSerum

Daily: AM | PM

Apply after 24/7 Barrier Balance Cream.

30 seconds after applying STEP TWO, place a pea-size amount of serum onto fingertips. While skin is still moist, lightly massage with fingertips first around eyes, then over entire face. Use a second drop on neck and décolleté. Follow with sunscreen.
Suitable for all skin types.



2-Minute Reveal Masque

1-2 Xs A WEEK | 2-Minute Reveal Masque

Once or twice a week after cleansing, dry skin thoroughly. Apply a dollop of masque about the size of a quarter to face and jawline. Using dry fingertips, gently massage masque in a circular motion for 20 seconds or less depending on skin sensitivity. Avoid eye area. Wait 2 minutes. With moistened fingertips, massage until crystals are completely dissolved. Rinse face thoroughly. Follow with STEP TWO (24/7 Barrier Balance Cream).
Not recommended for acne, extremely sensitive or abraded skin.

DefenAge is proven in 15 clinical studies. All DefenAge formulas in this kit are dermatologist tested. 8-in-1 BioSerum is also ophthalmologist tested.

Multi-center placebo-controlled double-blind clinical study shows that DefenAge’s Clinical Power Trio (a full size version of this kit) “globally improves the visual appearance of aging skin” and “offers most of the advantages of time-honored retinols as well as newer but widely used growth-factor containing cosmeceuticals, without irritation or inflammation, sun-sensitivity, or concerns about neoplasia of the treated skin.”
Journal of Drugs in Dermatology 2018, 17(4): p. 426-441Amy Taub MD, Vivian Bucay MD, Gregory Keller MD, Jay Williams PhD, and Darius Mehregan MD

Learn More ►



Age-Repair Defensins® | DefenAge's Exclusive

promotes new skin • anti-aging on a global scale

Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of "fresh" and young cells. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.


hydration • firmness & elasticity • brightening

Soothes, revives the skin’s natural moisture barrier, renews the feel of skin firmness and elasticity, and brightens overall skin tone.

Hyaluronic Acid

Liposome Encapsulated (Cream) | Low Molecular Weight (Serum)

• hydration •

Promotes hydration and improves texture for remarkably smooth and even skin.

Sea Whip

• skin calming & soothing •

Keeps skin calm. Strongest, fastest, most effective soothing ingredient from the sea.

Fine Blends of Natural Antioxidants, Enzymes

and Hydrating Technologies

antioxidants • hydration • soothing

Our “know-how”-protected, advanced and powerful blends of antioxidants and enzymes address environmental cell damage and defend against free radicals. They brighten, clarify and energize the skin for a revitalized radiance and luminosity.


All three products in the Fly Kit comply with clean skincare requirements. Learn more about DefenAge’s enhanced standards in clean cosmetics on our Clean Beauty page.


The tubes and box are fully recyclable, please recycle.

Not tested on animals.


The detailed ingredient lists can be found on the individual product pages:


24/7 Barrier Balance Cream | No Fragrance Added ►

8-in-1 BioSerum | No Fragrance Added ►



For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.



Quality guaranteed ONLY when sold by or authorized professionals, otherwise it may be counterfeit, black market, old or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay or other unauthorized sources. 



This product is qualified for the Money Back Guarantee.
Return Policy ►


Main Things to Look For in an Effective Travel Size Skincare Kit
When looking for the best travel-size skincare sets, here are a few things to pay attention to. Ingredients - Skin care products often have a long list of ingredients, and it may be difficult to know what they all are. The best thing you can do is pay attention to and learn about the active ingredients. How will these ingredients affect your skin? What is the product’s goal? A little research goes a long way when choosing the best products for your skin. Safe for skin - A skincare line that is safe for your skin should be one of your top priorities. Take a look at those ingredients again. Do you see any harsh chemicals listed? Avoid the harmful chemicals and opt for clean skincare ingredients such as the ones found in DefanAge products. Effective - If possible, find reviews of products before buying them. This will tell you if it is an effective product worth trying. Doctor approved - Reviews can offer a lot of insight, but not all positive reviews are equal. When looking for a new skincare line to try, check out what the experts are saying. Look for a skincare line that is recommended by doctors, such as our travel size skincare kit, to help you feel more comfortable using it. Cruelty-free - With today’s big lineup of skincare products, it’s possible to find a quality skincare product without having to compromise your feelings about animal testing. Find a cruelty-free skincare line to support a company that has the same values as you.
Can I Layer These Products With Other Products?
Yes! DefenAge products use defensin molecules as part of our anti-aging technology. This means these travel-size skincare products can be combined with almost any other skincare ingredient or product. This includes Retin-A and retinols, hyaluronic acid, vitamin C, and growth factors. Just be sure to layer all other skincare products prior to layering your Fly Kit products.
How Long Will It Take To See Results?
You can see initial results in as little as one week, while the full range of results can be seen in six weeks.
How Long Will These Products Last?
Our Fly Kit is a travel size of the Clinical Power Trio skincare set and is designed to be a two-week supply of each of these popular products.