8-IN-1 BIOSERUM | Pack of 3 | 2022

The 8-in-1 BioSerum is DefenAge's iconic bestseller. The remarkably smart formula seems to understand your skin’s needs better than your own DNA. Designed to activate, orchestrate and energize, this biologically-advanced anti aging cream-like serum concentrate provides an unprecedented concentration of defensin molecules contained in the Age-Repair Defensin^® Complex. Dermatologists and aesthetic professionals name defensins as a perfect retinol alternative and the 8-in-1 BioSerum as a retinol serum replacement. The best part? Results are equal to 8 separate serums. Apply with the 24/7 Barrier Balance Cream to create smoother, younger looking skin. Patented technology. Get the best skin ever today!

Expert opinions ►

• •  Rejuvenates smoothness. Improves overall visible skin health and quality.
• •  Minimizes the look of fine lines, wrinkles, pores, and skin pigmentation and discolorations.
• •  Promotes radiance and revives the skin’s natural moisture for an ultimate glow.
• •  Brightens the overall skin tone and clarity and enhances skin luminosity.
• •  Renews the feeling of skin firmness, elasticity, and texture.
• •  Helps improve the appearance of skin redness.
• •  Promotes the skin barrier and immunity.

Why it’s different

• •  Advanced targeted cosmetic treatment with an established and validated science. A unique mechanism of action.
• •  Contains 5 times more defensin-molecules than any other formulas.
• •  Light-weight application; “you don't feel it when you're wearing it”.
• •  Effective and safe for the entire face, including the delicate skin around the eyes and lips, and the neck and décolleté. High-performing on the crepey thin skin on the neck and arms.
• •  Fast acting anti-aging – first results are seen within a few weeks.
• •  Perfect as a daily skincare product for both men and women.
• •  Effective for both early and late stages of skin aging, including people above 70.
• •  Non-irritating and gentle on sensitive skin overall, and over retinols.
• •  Tolerated by all skin types. Good for rosacea and melasma patients, can be combined with other treatments for rosacea patients.
• •  Highly effective for pre- and post- aesthetic procedures to achieve the optimal outcomes, including microneedling and fractional and resurfacing/ablative laser treatments. Primes the skin to a quick and robust response. Optimizes healing and minimizes the risk of acne break-outs post-procedure.  
• •  Effective to prep the skin and enhance filler results, recommended to use 4-6 weeks before a filler procedure.
• •  DefenAge's most “likable” product with the most impressive consumer feedback.
• •  Mega size, 1.5 fl oz, is now available.

Made in the U.S.A.

10 specific ways leading dermatologists recommend using the 8-in-1 BioSerum:

1. For daily use. It’s lightweight. “You can’t even feel it when you’re wearing it.” Dermatologist Vivian Bucay, MD

2. For sensitive skin. It delivers anti-aging results but it’s “not irritating like a retinol or acids.” Dermatologist Anne Chapas, MD

3. For older age. Even old skin has young dormant cells that can be turned on by defensins. “We saw a marked difference at 2 months” in a 73-year-old patient. Dermatologist Angela Bowers, MD

4. For better skin quality, including firmer skin, fewer fine lines, more luminosity and clarity, and a reduced appearance of pores. Dermatologist Anne Chapas, MD

5. After microneedling, patients are “less likely to break out with acne post treatment.” Dermatologist Vivian Bucay, MD

6. “4 to 6 weeks before having filler procedures” to prep the skin and enhance results. Dermatologist Kathleen Welsh, MD

7. Before and after ablative skin treatments, which “primes skin to respond more quickly and robustly, healing faster.” Dermatologist Steven Swengel, MD

8. To target specific areas, including around the eyes and lips. Dermatologist Angela Bowers, MD

9. Beyond the face: on the neck and décolleté. Dermatologist Steven Swengel, MD

10. For crepey thin skin on the neck and arms. Dermatologist Kathleen Welsh, MD

Add an Anti Aging Cream to Your Skincare Regimen

Dermatologists agree, if you do one nice thing for your skin this year - introduce it to defensin-molecules. Defensins can be incorporated into your existing skincare regimen and do not conflict or compete with other skincare. Whether it’s CHANEL or Clinique, incorporating DefenAge + Defensins can actually enhance the skincare you already know and love.

Consumer survey says that 93% of consumers who use CHANEL

skincare also like the results they see with DefenAge!

/ Survey 2019, data on file /

“Why do CHANEL users like DefenAge? – this is simple – DefenAge’s defensins multiply the effect of other skincare. …Ironically, DefenAge skin care has no competition on the skincare market because it enhances any other skin care brands. Much like laser treatments and microneedling, the topical application of defensins causes our body to message ‘preserved,’ healthy cells to create visibly new skin. I recommend the BioSerum to my patients to activate their “skin’s memory”, triggering skin to look younger, twice a day – in the morning and evening by applying just one drop of DefenAge BioSerum over the moisturizer of their choice,”

-Board-certified dermatologist Natalie M. Curcio, M.D., M.P.H.

Check with us, what other skincare than CHANEL can be combined with DefenAge's defensins for more glowing skin.  

Opinions and Stories

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The 8-in-1 BioSerum, anti-aging serum, from DefenAge is a best-selling product with the highest concentration of Age-Repair Defensins. Defensins are molecules that prompt dormant cells to make brand-new, healthy skin cells. DefenAge is the only brand to use Age-Repair Defensins, a proprietary ingredient. The result is new skin cells that look younger and healthier. DefenAge’s products don’t merely cover signs of visible aging.