Pack of 3

Holiday PROMO ❄
Shop Gifts At DefenAge!

VALUE Pack of 3:
Third 6-Week Perfection Neck Cream in your shopping bag is FREE!

Limited time offer, until December 31st only or until supplies last.

You can earn 190 points in DefenAge® Skin Club with this purchase.


Pack of 3

Holiday PROMO ❄
Shop Gifts At DefenAge!

VALUE Pack of 3:
Third 6-Week Perfection Neck Cream in your shopping bag is FREE!

Limited time offer, until December 31st only or until supplies last.

You can earn 190 points in DefenAge® Skin Club with this purchase.

/ $190 with free account /

Neck Cream Award

Price above is shown for the bundle of 3 units (VALUE Pack of 3). Each unit in this bundle contains 1.5 fl oz (Full Size).

A luxe anti-aging neck tightening cream infused with leading scientific advances. Designed to correct the challenging deep lines, folds, and impacts of gravity on the fragile skin of the neck where aging is often more noticeable. Expert opinions


  • •  Reverses a comprehensive range of neck-specific visible signs of skin aging, designed to produce treatment-like results.
  • •  Soothes the look of deep lines and folds, visibly reduces fine lines, and gives the neck a smooth appearance.
  • •  Visibly lifts, firms, and tightens sagging neck skin.
  • •  Improves visible skin thickness. Brightens.
  • •  Softens and improves the surface skin texture.
  • •  Provides rich moisturization.
  • •  Leaves the neck looking, and feeling, youthful.


Why it’s different

  • •  Specifically designed for the skin of the neck, which ages differently than other parts of our skin.
  • •  Effective for both early and late stages of neck aging.
  • •  Fast acting – first results within 2 weeks, full range of results in 6 weeks.
  • •  Gentle on the sensitive neck skin over retinols.
  • •  A scientifically validated high-performing formula. 
  • •  Exceeds clean beauty standards. No PEGs, animal- or human-derived ingredients. Fragrance free.
  • •  Silky application and smooth luxurious texture. Spreads evenly without a “sticky” feeling.
  • •  Mega size: 1.5 oz +


Made in the U.S.A.



Opinions and Stories


It’s all about the neck.

by Veronica Webb, supermodel mom and influencer

Runway model, featured magazine cover star and the first African-American to earn major cosmetics contracts, Veronica Webb shares her insights for picture perfect skin. Read more ...



Correct the Look of Challenging Deep Lines with DefenAge’s Neck Tightening Cream

The 6-Week Perfection Neck Tightening Cream from DefenAge is formulated explicitly to target the skin on your neck. Neck-specific signs of aging such as deep lines and folds may seem challenging to combat or keep at bay. However, DefenAge’s neck tightening cream is scientifically validated to offer results. The powerful formula supports the visible texture of your skin using DefenAge’s propriety Age-Repair Defensins technology. You can target the delicate skin on your neck using this luxurious DefenAge formula and support the appearance of youthful-looking skin.



Neck Tightening Cream | 6-WEEK PERFECTION NECK CREAM by DefenAge

STEP TWO - NECK| 6-Week Perfection Neck Cream 

Daily: AM | PM

Twice daily after cleansing, place 1 pump of the neck tightening cream onto fingertips. While skin is still moist, lightly massage cream onto the skin with short lifting motions using fingers of right hand to apply to left side of neck and décolleté, and vice versa. Start above breast line and work up to jawline and back of neck. Wait 30 seconds, then apply 8-in-1 BioSerum | STEP THREE.

Suitable for all skin types.




For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.


The 6-Week Perfection Neck Cream is dermatologist tested.


It is a valuable addition to the DefenAge line to treat the fragile skin of the neck, which can typically get irritated from standard anti-aging creams like retinol. Using the advanced technology they have pioneered, the new neck cream can bring brightness, improve the visible thickness of the skin, and reduce the wrinkling on the neck where aging is often more noticeable,

- Dermatologist Amy Forman Taub, MD


“My favorite neck cream is the new 6-Week Perfection Neck Cream. Scientifically proven defensin molecules result in skin looks firmer, smoother, and more even toned."

- Dermatologist Vivian Bucay, MD


“Many neck creams have proprietary peptides addressing early laxity but with different ingredients. The combo of defensins, as well as peptides, in this product can be a game changer; the defensins’ entire impact on the epidermis is more than peptides alone. An increase in blood supply and dermal support to a more robust epidermis can be critical. A lot of early neck changes start with the epidermis and superficial dermis. I also recommend adding an extra pump of DefenAge’s 8-in-1 BioSerum to apply on the neck to my patients like I do with my own skin care regimen,"

- Dermatologist Steven Swengel, MD


“I have tried the DefenAge anti-aging neck cream twice a day for one week and love it. The texture is smooth, so it spreads easily and evenly. I love that it is very hydrating and it seems to immediately reduce visible fine lines, giving the neck a smooth appearance,”

- Dermatologist Melda Isaac, MD


“After just 11 days of my patients using the neck cream, I was impressed to see the softening of lines and skin texture, and a visible tightening effect,"

- Clinical Professor of Surgery at UCLA, Gregory Keller, MD


“The 6-Week Perfection Neck Cream has a very luxurious texture and is a superb moisturizer, and an excellent addition to the DefenAge product range that I recommend to my patients. They can also use it on their hands and arms,”

- Dermatologist Angela Bowers, MD


DefenAge does it again! Another great product harnessing their defensin technology. I’m excited to be able to add this new innovation to my portfolio and recommend DefenAge’s neck cream to my patients.

- Dermatologist Sue Ellen Cox, MD


“Finally, the neck cream we have all been waiting for, loaded with the defensin technology we know gives visible results that last. This light but luxurious-feeling cream is hydrating without the sticky feeling often associated with other neck creams. It goes on smoothly, leaving my neck looking and feeling more youthful,”

- Linda Pitt, Master Aesthetician, Signature Medical Spa


Source: Neck Tightening Cream Article | Modern Aesthetics Magazine ►



Age-Repair Defensins® | 1X  | DefenAge's Exclusive

promotes new skin • anti-aging on a global scale • retinol alternative

Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of "fresh" and young cells. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.


hydration • firmness & elasticity • brightening

Niacinamide soothes, revives the skin’s natural moisture barrier, renews the feel of skin firmness and elasticity, and brightens overall skin tone.


Sea Whip

• skin calming & soothing •

Keeps skin calm. Strongest, fastest, most effective soothing ingredient from the sea.

Fine Blends of Advanced Peptides and Natural Extracts

anti-wrinkle • hydration • visible tightening

Our “know-how”-protected, advanced, and powerful blends of peptides and natural extracts have been shown to be effective in visible tightening of sagging neck skin.



• skin-replenishing •

Energize skin hydration. One of nature’s most powerful retainers of moisturization.


Vitamin E

• antioxidant •

Proven antioxidant, address environmental cell damage and defend against free radicals. Clarify and energize the skin for a revitalized radiance and luminosity.



The neck cream formula exceeds most, if not all, industry and beauty standards for clean skincare. In addition to the extended list of ingredients that are restricted for use in DefenAge, the 6-Week Perfection Neck Tightening Cream also does not contain silicones, PEGs, and is free from fragrance. To learn more about DefenAge’s clean skincare standards, please visit our Clean Beauty page.


The jar-bottle and box are fully recyclable, please recycle.

Not tested on animals.


6-Week Perfection Neck Cream

Water (Aqua), Butyrospermum Parkii (Shea) Butter, C13-15 Alkane, Caprylic/ Capric Triglyceride, Propanediol, Niacinamide, Cetyl Alcohol, Phospholipids, Alpha-Defensin 5, Beta-Defensin 3, Leontopodium Alpinum Callus Culture Extract, Sea Whip Extract, Squalane, Simmondsia Chinensis (Jojoba) Seed Oil, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Leuconostoc/Radish Root Ferment Filtrate, Palmitoyl Tripeptide-5, Panthenol, Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5, Diaminohydroxybutyrate, Ubiquinone, Albumin, L-Alanyl-L-Glutamine, Tocopheryl Acetate, Palmitic Acid, Stearyl Alcohol, Sodium Stearyol Glutamate, Glycerin, Methyl Glucose Sesquistearate, Polysorbate 20, Polyacrylate Crosspolymer-6, Xanthan Gum, Butylene Glycol, Carbomer, Phytic Acid, Sodium Phytate, Caprylhydroxamic Acid, 1,2-Hexanediol, Sorbic Acid, Sodium Chloride.



Quality guaranteed ONLY when 6-Week Perfection Neck Cream is sold by defenage.com or authorized professionals, otherwise it may be counterfeit, black market, old or improperly stored or handled.
Quality is NOT guaranteed when sold by Amazon, eBay or other unauthorized sources. 



6-Week Perfection Neck Cream is qualified for the Money Back Guarantee.
Return Policy ►


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